3.A.2.1.12
F-type ATPase lacking a δ-subunit, but having another subunit, AtpR of 104 aas and 3 TMSs that may replace the δ-subunit. Has a c-subunit that shows the expected residues that comprise a Na+ binding site, so it may be a Na+ exporting ATPase. It is in a family of similar ATPases that all lack δ-subunits and have been called N-ATPases (Na+-transporting) (Dibrova et al. 2010). They appear to be subject to horizontal transfer and represent a second type of F-type ATPase, the other transporting protons. They are found in a variety of bacteria and archaea (Dibrova et al. 2010). The AtpQ protein may be a Mg2+ channel.
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| Accession Number: | Q467F6 |
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| Protein Name: | H(+)-transporting ATP synthase, subunit alpha |
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| Length: | 571 |
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| Molecular Weight: | 62933.00 |
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| Species: | Methanosarcina barkeri (strain Fusaro / DSM 804) [269797] |
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| Number of TMSs: | 2 |
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| Substrate |
sodium(1+) |
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1: METKGLKDVF DKVFTEIHQA RESVTPTLTP KEVGRILTVS TGIANVSGLP TVGFDELIKF
61: PGDLFGIAFN VDEKEIGTVL LGEYSHLHAG DQVERTQRVM DVAVGEELLG RVIDPLGRPL
121: DNKGPIVSSK RLPIERPSPA IMDRAPVTVP LQTGVKVIDA LIPIGRGQRE LILGDRQTGK
181: TAIAIDTILN QRNFNVLCVY CAIGQRASAV ARAVANLRER GAMDYTIVVV TEGNDPSGLI
241: YIAPYAATSI AEYFMEAGRD VLIVYDDLTN HARAYRELSL LLRRPPGREA YPGDIFYIHS
301: RLLERSTHLL KELGGGSLTA LPIIETEAQN ISAYIPTNLI SITDGQIYLS PSLFELGVLP
361: AVDVGKSVSR VGGKAQLAAY RAVAGDIKLA YSQFEELEAF TRFGARLDEN TRKLIEHGRR
421: IRALLKQPQN SPVPVPDQIV ILVALNAKLF DNVPLDKMGE AESSLRKAVP DIPADVRDRF
481: KGDKELSDKD RETILDIARK SLKPYQPNPE SESKPEAKTE ERSESETQNE ERSESETQNE
541: EITESETQTE EKTESETQNK GKSEPEAEEK S