3.A.15.2.1
The pilin secretion/fimbrial assembly system. The PilB and PilT ATPases act antagonistically in Type IV pilus function in Myxococcus xanthus. ATP binding and hydrolysis by PilT are essential for T4P extension while ATP binding and hydrolysis by PilB are essential for T4P retraction. Thus, PilB and PilT act at distinct steps in the T4P extension/retraction cycle (Jakovljevic et al., 2008).
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| Accession Number: | Q51528 |
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| Protein Name: | FimT |
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| Length: | 169 |
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| Molecular Weight: | 18958.00 |
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| Species: | Pseudomonas aeruginosa [287] |
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| Number of TMSs: | 1 |
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| Location1 / Topology2 / Orientation3: |
Cytoplasm1 |
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| Substrate |
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[1] “Identification of a gene, pilV, required for type 4 fimbrial biogenesis in Pseudomonas aeruginosa, whose product possesses a pre-pilin-like leader sequence.” Alm R.A. et.al. 7565109
[2] “Identification of two genes with prepilin-like leader sequences involved in type 4 fimbrial biogenesis in Pseudomonas aeruginosa.” Alm R.A. et.al. 8682785
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1: MVERSQRALT LTELLFALVL LGILGSLALP GMAAWLDGNR ERSVLHELSA SIQLGRTHAV
61: AYQRPVTLCP STDGRHCGSD WGEGWLLAED GGERLLVGRA LAKKERLLWN RSNRLRFLPS
121: GQLNIHNGRF LLCGRHTVAW QLILNRQGRL RTASARENRE KRELCRTSG