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3.A.15.2.1
The pilin secretion/fimbrial assembly system. The PilB and PilT ATPases act antagonistically in Type IV pilus function in Myxococcus xanthus. ATP binding and hydrolysis by PilT are essential for T4P extension while ATP binding and hydrolysis by PilB are essential for T4P retraction. Thus, PilB and PilT act at distinct steps in the T4P extension/retraction cycle (Jakovljevic et al., 2008).

Accession Number:Q51532
Protein Name:PilU aka PA0396
Length:382
Molecular Weight:42533.00
Species:Pseudomonas aeruginosa [287]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cytoplasm1
Substrate

Cross database links:

RefSeq: NP_249087.1   
Entrez Gene ID: 878362   
Pfam: PF00437   
BioCyc: PAER208964:PA0396-MONOMER   
KEGG: pae:PA0396   

Gene Ontology

GO:0005622 C:intracellular
GO:0005524 F:ATP binding
GO:0017111 F:nucleoside-triphosphatase activity
GO:0006810 P:transport

References (3)

[1] “Characterisation of a Pseudomonas aeruginosa twitching motility gene and evidence for a specialised protein export system widespread in eubacteria.”  Whitchurch C.B.et.al.   1676385
[2] “Characterization of a gene, pilU, required for twitching motility but not phage sensitivity in Pseudomonas aeruginosa.”  Whitchurch C.B.et.al.   7854122
[3] “Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.”  Stover C.K.et.al.   10984043

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence 
1:	MEFEKLLRLM VEKGGSDLFI TAGVPPSMKV NGRVMPVTKT PLSPEQTRET VLGVMNEQQR 
61:	RDFAENHECN FAISARGIGR FRVSAFYQRN LVGMVLRRIE TNIPTLEELK LPEILKKLAL 
121:	TKRGLVIFVG ATGTGKSTSL AAMIGYRNKN STGHIISIED PIEYIHQHQG CIVTQREVGL 
181:	DTDSFEVALK NTLRQAPDVI MIGEVRSRET MDHAVAFAET GHLCLATLHA NNANQALERI 
241:	IHFFPADRHG QVWMDLSLNL KAIVAQQLVP TPDGKGRRAV IEVLLNTPLA ADLIRKGEVH 
301:	ELKPLMKRST EQGMQTFDQA LYQLYTQGEI TYEDALAHAD SANDLRLMIK LGSESDADHL 
361:	SSLTQGLSLE ITDDDPAGRR FR