Search TCDB: (?)
TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.63.1.1
Multicomponent K+:H+ antiporter, PhaABCDEFG. Can also transport Na+ (Yamaguchi et al., 2009).

Accession Number:Q52981
Protein Name:PhaD
Length:539
Molecular Weight:56303.00
Species:Rhizobium meliloti (Sinorhizobium meliloti) [382]
Number of TMSs:17
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate sodium(1+), potassium(1+), hydron

Cross database links:

RefSeq: NP_387018.1   
Entrez Gene ID: 1234589   
Pfam: PF00361   
BioCyc: SMEL266834:SMC03181-MONOMER   
KEGG: sme:SMc03181   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0008137 F:NADH dehydrogenase (ubiquinone) activity
GO:0015386 F:potassium:hydrogen antiporter activity
GO:0042773 P:ATP synthesis coupled electron transport
GO:0006813 P:potassium ion transport
GO:0015992 P:proton transport

References (2)

[1] “The pha gene cluster of Rhizobium meliloti involved in pH adaptation and symbiosis encodes a novel type of K+ efflux system.”  Putnoky P.et.al.   9680201
[2] “Analysis of the chromosome sequence of the legume symbiont Sinorhizobium meliloti strain 1021.”  Capela D.et.al.   11481430

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence 
1:	MTDWLDHLLI LPILLPLAVA AVLIPINERD RTLKGAIGFA STLVVFILSM ILMRLAAAGT 
61:	GSLPGSGVYQ LGNWPAPFGI VLVLDRLSAL MLCLTSGLAL AAQAYSMARW HTAGHHFHSL 
121:	FQLLVAGLNG AFLTGDLFNL FVFFEMMLAA SYGLLLHGSG PLRVKAGLHY IAVNLAASAL 
181:	FLIGVSLIYG AAGTLNMADL ATKLAALEPR SRTLVEMGSA ILGVAFLVKA GMWPLSFWLP 
241:	TAYAAATPPV AGVFAVLTKV GIYVIIRLHL LVFGTAAGAS SGFGQEWLVT GGMLTIAFGG 
301:	IGVLASQAMG RLAGYSVLVS SGTLLAAVGL GHDGMLAGAL FYLVSSTLTI GAFFLLIELV 
361:	ERGRDAGADV LAVTMEAYGD FDEDEEEEEV GAAIPGTMAV LGLCFCLCAL LLAGLPPLSG 
421:	FIAKFALISG LFDMPAAELA TAMSAADWTY VTLLILSGLA AMIAMNRIGI RTFWASIEGT 
481:	IPRVVVIEIT PVVVLLGACI FLSLQAGPAM RYMQATADDL LAPLTHSERV LSAPRAGSQ