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|---|---|
| Accession Number: | Q56019 |
| Protein Name: | SipB aka STM2885 |
| Length: | 593 |
| Molecular Weight: | 62451.00 |
| Species: | Salmonella typhimurium, and OS Salmonella dublin [90371] |
| Number of TMSs: | 3 |
| Location1 / Topology2 / Orientation3: | Secreted1 / Multi-pass membrane protein2 |
| Substrate | protein polypeptide chain |
Cross database links:
| RefSeq: | NP_461806.1 |
|---|---|
| Entrez Gene ID: | 1254408 |
| BioCyc: | STYP99287:STM2885-MONOMER |
| KEGG: | stm:STM2885 |
Gene Ontology | |
References (9)[1] “Homologs of the Shigella IpaB and IpaC invasins are required for Salmonella typhimurium entry into cultured epithelial cells.” Kaniga K.et.al. 7608068 [2] “Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.” McClelland M.et.al. 11677609 [3] “Salmonella typhimurium secreted invasion determinants are homologous to Shigella Ipa proteins.” Hueck C.J.et.al. 8748032 [4] “The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1.” Hersh D.et.al. 10051653 [5] “Membrane fusion activity of purified SipB, a Salmonella surface protein essential for mammalian cell invasion.” Hayward R.D.et.al. 10972796 [6] “The Salmonella type III secretion translocon protein SspC is inserted into the epithelial cell plasma membrane upon infection.” Scherer C.A.et.al. 10972831 [7] “Salmonella type III secretion-associated protein InvE controls translocation of effector proteins into host cells.” Kubori T.et.al. 12169593 | |
| Structure: | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MVNDASSISR SGYTQNPRLA EAAFEGVRKN TDFLKAADKA FKDVVATKAG DLKAGTKSGE 61: SAINTVGLKP PTDAAREKLS SEGQLTLLLG KLMTLLGDVS LSQLESRLAV WQAMIESQKE 121: MGIQVSKEFQ TALGEAQEAT DLYEASIKKT DTAKSVYDAA TKKLTQAQNK LQSLDPADPG 181: YAQAEAAVEQ AGKEATEAKE ALDKATDATV KAGTDAKAKA EKADNILTKF QGTANAASQN 241: QVSQGEQDNL SNVARLTMLM AMFIEIVGKN TEESLQNDLA LFNALQEGRQ AEMEKKSAEF 301: QEETRKAEET NRIMGCIGKV LGALLTIVSV VAAVFTGGAS LALAAVGLAV MVADEIVKAA 361: TGVSFIQQAL NPIMEHVLKP LMELIGKAIT KALEGLGVDK KTAEMAGSIV GAIVAAIAMV 421: AVIVVVAVVG KGAAAKLGNA LSKMMGETIK KLVPNVLKQL AQNGSKLFTQ GMQRITSGLG 481: NVGSKMGLQT NALSKELVGN TLNKVALGME VTNTAAQSAG GVAEGVFIKN ASEALADFML 541: ARFAMDQIQQ WLKQSVEIFG ENQKVTAELQ KAMSSAVQQN ADASRFILRQ SRA