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3.A.1.1.51
Maltose - maltoheptaose transporter, MalEFGK.  MalEF is a R-M fusion protein with the MalE domain N-terminal and the MalF domain C-terminal. The protein, of 733 aas, has 8 TMSs, one N-terminal to MalE (a signal sequence for export of the MalE domain to the periplasm), an extra TMS at the N-terminus to bring the N-terminus to the periplasmic side of the inner membrane, and then the usual 6 TMSs observed for many ABC membrane proteins.  MalG (M, 272 aas, 6 TMSs) and MalK (C, 374 aas) are of normal size and composition. While MalE of E. coli was able to additionally increase ATPase activity of MalFGK2 in vitro, the isolated MalE domain of B. bacteriovorus failed to stimulate the E. coli system (Licht et al. 2018). The adjacent genes are an α-amylase (Q6MNM3) and a glucokinase (Q6MNM4).

Accession Number:Q6MNM1
Protein Name:ABC-type Maltose/ Maltodextrin permease
Length:272
Molecular Weight:30570.00
Species:Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIB 9529 / HD100) [264462]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Maltose, Maltotriose, Maltotetrose, Maltopentose, Maltohexose, Maltoheptose, Trehalose

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FASTA formatted sequence
1:	MLKKTFSWIS ILLFSLFSIY PILYVLSVSL RPDNAFQTQS LEIIGPNASF KNFVDLFATT 
61:	DFLIWMRNSL VVSAATTLLG VALASTSAYA LARYRFRGRN MMLFSLLMTQ MFPATMLMLP 
121:	FYIILSKLRL IDSFWGLFLI YSSTALPFCI WQMKAYYDTI PRELEEAALL DGCSKWMIFY 
181:	KIILPVSSPA LVITALFSFM SSWSEYVIAA VVLQDPQLYT LPLGLRSFQA SLATQWGLYA 
241:	AGALIVSVPV LILFISISRY LVSGLTMGSV KG