1.A.9.1.12 Nicotinic acetylcholine receptor with three subunits, non-alpha subunit ShAR2beta of 545 aas, as well as two additional "non-alpha subunits of 714 and 736 aas, respectively, all with 6 TMSs, 1 N-terminal, 4 central, and 1 C-terminal (Bentley et al. 2007).
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Accession Number: | Q6TMY2 |
Protein Name: | Nicotinic acetylcholine receptor non-alpha subunit |
Length: | 736 |
Molecular Weight: | 84341.00 |
Species: | Schistosoma haematobium (Blood fluke) [6185] |
Number of TMSs: | 4 |
Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
Substrate |
inorganic cation |
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1: MNTLCHILCY IVLYQILCIT WIGKVDSGHS EKRLLKYLFD QKRWDAHNPM ERPVSVDGKP
61: VQVFLKCFLN QIMDVDEKNQ VLSTIIWLDL KWSDYHFHWN ASDYENIRQI NLPPERIWKP
121: DILLYNSASE KFDQIFPTKV IVRNTGNIQW VPPGLFHSIC DIEVNWFPFD SQNCIMKLGT
181: WTYQGNTVDL KLQCDNETED VDQPCHYMND VDLSTYLAHS EWALESASIK RNIQTYGGED
241: QTYIDVTIYV YMQRRALYYM FNIIIPCMIM SMMALLVFTL PPEANEKIVL GVTTLLSLTM
301: LLQLVADKLP QTSSGNPVLV LYFTCTMILC SLSLVCAVVL LNCHHHTGGI VYVPWWIETL
361: INIWLASILR IDHDLSDPNN NDNNNHHGDN NNNKTEPNLK NSKEKLIPSE NSFQLDQYDY
421: DKINHHIHLN HSYNNNSGNG NNNARNATVW SNIIDMNSEF RPAIVIHKPF KHDNNHNSNM
481: KKSLFMNQFK LKSELQSRIQ QNYFIDLDPD YDRDRGDQHQ LSTDLSGKPL NNMPYHTITT
541: TTIPEDRGNS RTNATSRLQY TCKRNLTEKS KYFNKTIPRF HLSSSSSSSS SNESPQDSSL
601: SSSPTPLPPA SSSSSSSSSS SSSRSTVFSS PNRITDPSSS SPFKQNHNNN DSMNFDIILL
661: KLKQISNELR FITSDMHNKD KEIKTSNQWR LACRVLDRLC LLIFTALNLF TTLGILTSAP
721: TVIKAFTSRG APSQPM