1.A.9.1.12 Nicotinic acetylcholine receptor with three subunits, non-alpha subunit ShAR2beta of 545 aas, as well as two additional "non-alpha subunits of 714 and 736 aas, respectively, all with 6 TMSs, 1 N-terminal, 4 central, and 1 C-terminal (Bentley et al. 2007).
|
Accession Number: | Q6TMY3 |
Protein Name: | Nicotinic acetylcholine receptor alpha subunit |
Length: | 714 |
Molecular Weight: | 81316.00 |
Species: | Schistosoma haematobium (Blood fluke) [6185] |
Number of TMSs: | 6 |
Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
Substrate |
inorganic cation |
---|
1: MLIMNSIIKL CFGLFMFIDV VLSGLYEKRL LKYLFDSSRP DAHNPIERPS ANDTETLNVS
61: VKFFLNQVMD VDEKNQVLTT IIWMDLIWND YHFLWNPKEF GNITTLNLPY TAVWRPDILL
121: YNCADEKFDR TFPTNTIIKH DGTVQWMPPG LFKSTCNIDI LWFPFDEQSC ILKFGSWTYY
181: GDQINFQLQC INASQPDCTQ VGTVDLSEYS RNGEFHLSGS SVRRYAQRYE CCDYDFVDVK
241: IAITLQRRAL YYVFNLIVPC LLISGMALMV FMLPPDAGEK ISLGVTILLS LTMFLQLVAD
301: KLPQTSEAIP LIGIYFSCTM FMCSLSIVFT VLVLNYHHRS ADCIAVPAWI RNIVNTYLAK
361: LMCMEPPKRS QIIEVEDISS SISDNFMENY PNTKKSQNET LIKGGARGEQ QQQQEGGGGE
421: EEDDEEGHIG AKTFVGWNYD TTNMMNSNIN PVYMKKHLFT NSPICINGNL KTTTLPMINQ
481: SMNNIDYQLH NTVNERTPKN AIANVIDLDD DFRATARFGN TTTTTTNTTH TTTTTHTNNS
541: NIFINMHEKQ TILNNNTKLK MNTDLLSSVT VTNQSLTVQS PYRLYNSVGN FNSKSVPLTP
601: ISTLEHVQNV FPDEFSDLSK NGVSFDRQIE PDPLSISIDL LNLYKPDLEI IINELHFITK
661: KLRDNEKESL ISLEWKFAAR VIDRFCLVIF SVCNIVVTFA ILCSAPNLIA SFMP