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2.A.6.2.31 Multidrug efflux pump, SdeAB-HasF (mediates fluoroquinolone efflux) (Begic and Worobec, 2008) (HasF is > 60% identical to TolC of E. coli (1.B.17.1.1))
Accession Number:	Q79MP5
Protein Name:	SdeA
Length:	395
Molecular Weight:	42816.00
Species:	Serratia marcescens subsp. marcescens [211759]
Number of TMSs:	1
Location¹ / Topology² / Orientation³:	Nucleus¹
Substrate	fluoroquinolone antibiotic

Pfam:	PF00529
Gene Ontology GO:0016020 C:membrane GO:0008565 F:protein transporter activity GO:0009306 P:protein secretion
References (1) [1] “Cloning, sequencing, and characterization of the SdeAB multidrug efflux pump of Serratia marcescens.” Kumar A.et.al. 15793131

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MANQPNSSFN AGGRTRAVAL GQRLSGVALL AALLAGCDNS VAHNAPPPPP VVSAASVVVK 
61:	PISQWDAFNG RVEAVQSVQL RPRVSGYIER VNYTEGDEVK KGQVLFTIDD RTYRAAREQA 
121:	QAELVRARNQ AALARSESSR TEKLIGTQAI SQEVWEQRRS SAAQAQSNVL AAQAQLDMAQ 
181:	LNLDFTRVTA PIDGRASRAM ITAGNLVTAG DSASVLTTLV SLDKVYVYFD VDEATFLRYQ 
241:	QQGRHDARLP VKVGLVGEDG TPHQGLVDFT DNQLNAGTGT IRMRALLDNR DRRFTPGLFA 
301:	RVQMPGSAEF NAMLIDDKAV MTDQNRKFVY IVDKDGKAQR RDIDVGRMAE GLRIVQKGLA 
361:	NGDRVIVDGM QKVFMPGMPV DAKSVAMTTT ASALN

2.A.6.2.31
Multidrug efflux pump, SdeAB-HasF (mediates fluoroquinolone efflux) (Begic and Worobec, 2008) (HasF is > 60% identical to TolC of E. coli (1.B.17.1.1))

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

2.A.6.2.31Multidrug efflux pump, SdeAB-HasF (mediates fluoroquinolone efflux) (Begic and Worobec, 2008) (HasF is > 60% identical to TolC of E. coli (1.B.17.1.1))

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

2.A.6.2.31
Multidrug efflux pump, SdeAB-HasF (mediates fluoroquinolone efflux) (Begic and Worobec, 2008) (HasF is > 60% identical to TolC of E. coli (1.B.17.1.1))