| |
|---|---|
| Accession Number: | Q80W99 |
| Protein Name: | Cation channel sperm-associated protein 3 aka Catsper3 |
| Length: | 395 |
| Molecular Weight: | 45486.00 |
| Species: | Mus musculus (Mouse) [10090] |
| Number of TMSs: | 5 |
| Location1 / Topology2 / Orientation3: | Cell projection1 / Multi-pass membrane protein2 |
| Substrate | calcium(2+) |
Cross database links:
| RefSeq: | NP_084048.1 |
|---|---|
| Entrez Gene ID: | 76856 |
| Pfam: | PF00520 |
| KEGG: | mmu:76856 |
Gene Ontology
GO:0001669
C:acrosomal vesicle
GO:0005929
C:cilium
GO:0005783
C:endoplasmic reticulum
GO:0020017
C:flagellar membrane
GO:0016021
C:integral to membrane
GO:0005227
F:calcium activated cation channel activity
GO:0005262
F:calcium channel activity
GO:0005515
F:protein binding
GO:0005244
F:voltage-gated ion channel activity
GO:0006816
P:calcium ion transport
GO:0030154
P:cell differentiation
GO:0001539
P:ciliary or flagellar motility
GO:0007275
P:multicellular organismal development
GO:0006814
P:sodium ion transport
GO:0030317
P:sperm motility
GO:0007283
P:spermatogenesis
GO:0055085
P:transmembrane transport
| |
References (6)[1] “All four CatSper ion channel proteins are required for male fertility and sperm cell hyperactivated motility.” Qi H.et.al. 17227845 [2] “The transcriptional landscape of the mammalian genome.” Carninci P.et.al. 16141072 [3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [4] “Catsper3 and catsper4 encode two cation channel-like proteins exclusively expressed in the testis.” Jin J.-L.et.al. 16107607 [5] “Expression of CatSper family transcripts in the mouse testis during post-natal development and human ejaculated spermatozoa: relationship to sperm motility.” Li H.-G.et.al. 17347248 [6] “Catsper3 and catsper4 are essential for sperm hyperactivated motility and male fertility in the mouse.” Jin J.-L.et.al. 17344468
| |
External Searches:
|
Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
|
|||
1: MSQHFHHNPV RVKSGSLFAT ASEALQARLS KIKRKDKECQ AYFRKVIKST FFQIVMITTV 61: TTNSFLLVLG TNYDIQFEFF RTFEVSELFF VSVYVCEFLM KVYVDPITYW KDGYNILDVI 121: ILIILTIPYL LRKIKGNHSA YLHFADGIQS LRILKLISYS RGIRTLIIAV GETVYTVASV 181: LTLLFLLMFV FAILGFCLFG VTDRGDLENW GNLASAFFTL FSLATVDGWT DLQEELDKRK 241: FTVSRAFTIL FILLASFIFL NMFVGVMIMH TEDSMKKFER DLTLERNLAI MEEKQIILKR 301: QQEEVNRLMN TQKSGSMNFI DMVEGFKKTL RHTDPMVLDD FSTSLSFIDI YLVTLDNQDV 361: IVSKLQELYC EIVNVLSLML EDMPKESSSS LSGLS