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2.A.6.2.26 The multidrug efflux pump, VmeAB-VpoC (Matsuo et al., 2007). There are 11 RND-type efflux transporters in Vibrio parahaemolyticus, and several (VmeCD, VmeEF and VmeYZ) contribute not only to intrinsic drug resistance but also to virulence (Matsuo et al. 2013).
Accession Number:	Q87SJ8
Protein Name:	VpoC
Length:	442
Molecular Weight:	47983.00
Species:	Vibrio parahaemolyticus [670]
Number of TMSs:	1
Location¹ / Topology² / Orientation³:	Secreted¹
Substrate	drug

RefSeq:	NP_796804.1
Entrez Gene ID:	1187893
Pfam:	PF02321
BioCyc:	VPAR223926:VP0425-MONOMER
KEGG:	vpa:VP0425
Gene Ontology GO:0019867 C:outer membrane GO:0005215 F:transporter activity GO:0015031 P:protein transport
References (1) [1] “Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism distinct from that of V. cholerae.” Makino K.et.al. 12620739

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MKKLLPLFIS AALGGISSSA WADSLAEIYD LAKQNDPQLL SVAAQRDRAF EAITSSRSAL 
61:	LPQINLTAGY NLTRGDTEYD SNLISDVSND SNALTAGVNF SQELYNRASW ITLDTAEKSA 
121:	RQADATYAAA QQGLILRVSQ AYFEVLRAQD NLVFVRAEKA AVGRQLEQTK QRFEVGLSAI 
181:	TDVHDAQAQY DAVLADEVLA ENDLINSYES LREITGQEHK NLNVLDTNRF SATRTNSPAE 
241:	TLIDEAKTKN LSLLSARISQ DIARDNISLA SSGHLPTLSL DGGYNYGDTS NSARDNTTDN 
301:	FNIGVNLAVP LYTGGNVTSQ TKQAEFAYVA ASEDLEAQYR SVVKDVRAQN NNINASIGAL 
361:	KAYEQSVVSA RSALEATEAG FDVGTRTIVD VLDATRRLYD ANKNLSDARY NYILSVLQLR 
421:	QAVGTLSEQD ILDVDAGLKP AK

2.A.6.2.26
The multidrug efflux pump, VmeAB-VpoC (Matsuo et al., 2007). There are 11 RND-type efflux transporters in Vibrio parahaemolyticus, and several (VmeCD, VmeEF and VmeYZ) contribute not only to intrinsic drug resistance but also to virulence (Matsuo et al. 2013).

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

2.A.6.2.26The multidrug efflux pump, VmeAB-VpoC (Matsuo et al., 2007). There are 11 RND-type efflux transporters in Vibrio parahaemolyticus, and several (VmeCD, VmeEF and VmeYZ) contribute not only to intrinsic drug resistance but also to virulence (Matsuo et al. 2013).

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

2.A.6.2.26
The multidrug efflux pump, VmeAB-VpoC (Matsuo et al., 2007). There are 11 RND-type efflux transporters in Vibrio parahaemolyticus, and several (VmeCD, VmeEF and VmeYZ) contribute not only to intrinsic drug resistance but also to virulence (Matsuo et al. 2013).