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|---|---|
| Accession Number: | Q8BVN3 |
| Protein Name: | Cation channel sperm-associated protein 4 aka CatSper4 |
| Length: | 442 |
| Molecular Weight: | 51130.00 |
| Species: | Mus musculus (Mouse) [10090] |
| Number of TMSs: | 6 |
| Location1 / Topology2 / Orientation3: | Cell projection1 / Multi-pass membrane protein2 |
| Substrate | calcium(2+) |
Cross database links:
| RefSeq: | NP_001123502.1 NP_808534.1 |
|---|---|
| Entrez Gene ID: | 329954 |
| Pfam: | PF00520 |
| KEGG: | mmu:329954 |
Gene Ontology
GO:0001669
C:acrosomal vesicle
GO:0005929
C:cilium
GO:0020017
C:flagellar membrane
GO:0016021
C:integral to membrane
GO:0005227
F:calcium activated cation channel activity
GO:0005262
F:calcium channel activity
GO:0005515
F:protein binding
GO:0005244
F:voltage-gated ion channel activity
GO:0006816
P:calcium ion transport
GO:0030154
P:cell differentiation
GO:0001539
P:ciliary or flagellar motility
GO:0007275
P:multicellular organismal development
GO:0006814
P:sodium ion transport
GO:0030317
P:sperm motility
GO:0007283
P:spermatogenesis
GO:0055085
P:transmembrane transport
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References (7)[1] “The transcriptional landscape of the mammalian genome.” Carninci P.et.al. 16141072 [2] “Lineage-specific biology revealed by a finished genome assembly of the mouse.” Church D.M.et.al. 19468303 [3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [4] “Catsper3 and catsper4 encode two cation channel-like proteins exclusively expressed in the testis.” Jin J.-L.et.al. 16107607 [5] “Expression of CatSper family transcripts in the mouse testis during post-natal development and human ejaculated spermatozoa: relationship to sperm motility.” Li H.-G.et.al. 17347248 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MSEKHKWWQQ VENIDITHLG PKRKAYELLG RHEEQVLINR RDVMEKKDAW DVQEFITQMY 61: IKQLLRHPAF QLLLAFLLLS NAITIALRTN SYLGQKHYEL FSTIDDIVLT ILICEVLLGW 121: LNGFWIFWKD GWNILNFAIV FILFMGFFIK QLDMVAITYP LRVLRLVHVC MAVEPLARII 181: KVILQSMPDL ANVMALILFF MLVFSVFGVT LFGAFVPKHF QNMGVALYTL FICITQDGWL 241: DIYTDFQMDE REYAMEVGGA IYFAVFITLG AFIGLNLFVV VVTTNLEQMM KTGEEEGHLN 301: IKFTETEEDE DWTDELPLVH CTEARKDTST VPKEPLVGGP LSNLTEKTCD NFCLVLEAIQ 361: ENLMEYKEIR EELNMIVEEV SSIRFNQEQQ NVILHKYTSK SATFLSEPPE GANKQDLITA 421: LVSREKVSDS NINMVNKHKF SH