3.A.1.5.36 Peptide transporter encoded adjacent to the putative transport system with TC#3.A.1.5.35 (Akanuma et al. 2011). Induced by exogenous S-adenosylmethionine (SAM) at a concentration of 2muM which also enhanced antibiotic production and inhibited morphological development (Park et al. 2005). SAM can be imported into cells. Mutants in the bldK genes confer resistance to the toxic tripeptide, bialaphos (Nodwell et al. 1996).
|
Accession Number: | Q8CJS2 |
Protein Name: | Putative peptide transport system ATP-binding subunit |
Length: | 381 |
Molecular Weight: | 41788.00 |
Species: | Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) [100226] |
Substrate |
peptide |
---|
1: MSDNSKTTTA VADDFPQQRD GDTAPLLKVS GLSKHFPIKG GFPIKRTVGH VKAVDGVDFE
61: VFPGESLGLV GESGCGKSTT GRLLTRLYEP TQGSIEYRGK DITRANRREL APVRSEIQMI
121: FQDPYASLNP RQTVGTIISG PMEINGINPP GGREKRVREL LEIVGLNPEH YNRFPHEFSG
181: GQRQRIGVAR AVALQPKLIV ADEPVSALDV SIQAQVVNLL QEVQREMGIA FVFIAHDLAI
241: VRHFSQRVAV MYLGKIVEIA DRDSLYNRPR HPYTHALLSA VPETDLDAEK RERIRLEGDV
301: PSPISPPSGC RFRTRCWKAQ DKCATEEPPL VQLSGNREGH LTACHFPEEG STEARAEDIV
361: MDPGLKAMED GADGGATLSK G