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3.A.7.15.1
The nonspecific tight adherence fibril (pilus) secretion septum (Flp-1, Flp-2, TadV-RcpCAB Tad ZA-G) (Kachlany et al., 2000; Bhattacharjee et al., 2001; Haase et al., 2003; Schreiner et al., 2003; Wang and Chen, 2005; Tomich et al. 2007). The outer membrane components of the Tad (tight adherence) secreton have been identified (Clock et al. 2008). The tad locus is required for tenacious, nonspecific adherence to surfaces and formation of extremely strong biofilms. This locus is dedicated to the biogenesis of Flp pili, which are required for colonization and virulence (Perez et al. 2006).

Accession Number:Q8GCZ9
Protein Name:TadZ
Length:374
Molecular Weight:41681.00
Species:Actinobacillus actinomycetemcomitans (Haemophilus actinomycetemcomitans) [714]
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate protein polypeptide chain

Cross database links:

References (2)

[1] “Genes for tight adherence of Actinobacillus actinomycetemcomitans: from plaque to plague to pond scum.”  Kachlany S.C.et.al.   11553455
[2] “The Widespread Colonization Island of Actinobacillus actinomycetemcomitans.”  Planet P.J.et.al.   12717435

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MLLLDQETIT ADSARTITIV SSRDDIQGEV AQILRTRGLE NIEIVKKDFF TSSDEISFSA 
61:	EDTVGVIIDI THETNIKTIV ERVFSIVPQN VWCCVIGDSD SISLSQKLLD EGILYFNSHT 
121:	QLSQMVEKII LGVDIPRLRD TVKIAVLSCK GGIGASLISS HIANEIVSSK KIPVLLAQGP 
181:	NGSQDLDLLF DKKLSGNVIE YTPNLDIFNG SLFELTPAAT EKYNFIIYDQ PIYNVKKDNF 
241:	IGFLENYNSF VLVVERRIGS LRLAKQFLDE CERIRSTSRK PIRTFVCISD NRMESAKLMA 
301:	KNDIETLIGS SIDAVIPYIK NTNTKTVLGI NLGRDGKKEI NSLMLKVIGA ISRSSKPKEK 
361:	QSLFSSFFSK LIKQ