Search TCDB: (?)
TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.A.7.15.1
The nonspecific tight adherence fibril (pilus) secretion septum (Flp-1, Flp-2, TadV-RcpCAB Tad ZA-G) (Kachlany et al., 2000; Bhattacharjee et al., 2001; Haase et al., 2003; Schreiner et al., 2003; Wang and Chen, 2005; Tomich et al. 2007). The outer membrane components of the Tad (tight adherence) secreton have been identified (Clock et al. 2008). The tad locus is required for tenacious, nonspecific adherence to surfaces and formation of extremely strong biofilms. This locus is dedicated to the biogenesis of Flp pili, which are required for colonization and virulence (Perez et al. 2006).

Accession Number:Q8GD02
Protein Name:TadV
Length:142
Molecular Weight:15818.00
Species:Actinobacillus actinomycetemcomitans (Haemophilus actinomycetemcomitans) [714]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate protein polypeptide chain

Cross database links:

Pfam: PF01478   

Gene Ontology

GO:0016020 C:membrane
GO:0004190 F:aspartic-type endopeptidase activity

References (2)

[1] “Genes for tight adherence of Actinobacillus actinomycetemcomitans: from plaque to plague to pond scum.”  Kachlany S.C.et.al.   11553455
[2] “The Widespread Colonization Island of Actinobacillus actinomycetemcomitans.”  Planet P.J.et.al.   12717435

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence 
1:	MNWVINALVI ITLLLLITLS VTDIRSRLIS NRVVLFLLFV IVPFSLLKYQ TIFVIPALCT 
61:	LIIGFLLFSL HFIGAGDVKL VSVLMLAVPS DEIFSFFFFT TFAGLGLIII GWLFFRKSIK 
121:	ENGLPYGVAI SLGFMINLAL SN