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3.A.1.24.3
The methionine porter, AtmBDE (Sperandio et al., 2007)

Accession Number:Q8K8K7
Protein Name:AtmE
Length:230
Molecular Weight:24868.00
Species:Streptococcus pyogenes serotype M3 GN=atmE PE=3 SV=1 [301448]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Methionine

Cross database links:

HEGENOM: HBG592565
RefSeq: NP_664039.1    NP_802886.1   
Entrez Gene ID: 1008549    1066436   
Pfam: PF00528   
BioCyc: SPYO193567:SPS1624-MONOMER    SPYO198466:SPYM3_0235-MONOMER   
KEGG: spg:SpyM3_0235    sps:SPs1624   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0006810 P:transport

References (2)

[1] “Genome sequence of a serotype M3 strain of group A Streptococcus: phage-encoded toxins, the high-virulence phenotype, and clone emergence.”  Beres S.B.et.al.   12122206
[2] “Genome sequence of an M3 strain of Streptococcus pyogenes reveals a large-scale genomic rearrangement in invasive strains and new insights into phage evolution.”  Nakagawa I.et.al.   12799345

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSQLIQTYLP NVYELGWSGD AGWGLAIWNT LYMTIVPFIV GGAIGLLLGL LLVLTGPDGV 
61:	IENKTICWVI DKVTSIFRAI PFVILIAILA SFTYLLLRTT LGATAALVPL TFATFPFYAR 
121:	QVQVVFSELD KGVIEAAQAS GATFWDIVKV YLSEGLPDLI RVSTVTLISL VGETAMAGAI 
181:	GAGGLGNVAI SYGYNRFNND VTWVATIIIL LIIFAIQFIG DSLTRRFSHK