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3.A.1.24.3
The methionine porter, AtmBDE (Sperandio et al., 2007)

Accession Number:Q8K8K8
Protein Name:AtmD (MetN)
Length:354
Molecular Weight:38922.00
Species:Streptococcus pyogenes serotype M3 GN=metN PE=3 SV=1 [301448]
Location1 / Topology2 / Orientation3: Cell membrane1 / Peripheral membrane protein2
Substrate Methionine

Cross database links:

HEGENOM: HBG758042
RefSeq: NP_664038.1    NP_802887.1   
Entrez Gene ID: 1008548    1065156   
Pfam: PF00005    PF09383   
BioCyc: SPYO193567:SPS1625-MONOMER    SPYO198466:SPYM3_0234-MONOMER   
KEGG: spg:SpyM3_0234    sps:SPs1625   

Gene Ontology

GO:0005886 C:plasma membrane
GO:0015424 F:amino acid-transporting ATPase activity
GO:0005524 F:ATP binding
GO:0015821 P:methionine transport

References (2)

[1] “Genome sequence of a serotype M3 strain of group A Streptococcus: phage-encoded toxins, the high-virulence phenotype, and clone emergence.”  Beres S.B.et.al.   12122206
[2] “Genome sequence of an M3 strain of Streptococcus pyogenes reveals a large-scale genomic rearrangement in invasive strains and new insights into phage evolution.”  Nakagawa I.et.al.   12799345

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MNEAIIQLDH IDITFRQKKR VIEAVKDVTV HINQGDIYGI VGYSGAGKST LVRVINLLQA 
61:	PTNGKITVDG DVTFEQGKVQ LSANALRQKR RDIGMIFQHF NLMAQKTAKE NVAFALRHSS 
121:	LSKTEKEHKV IELLELVGLS ERADNYPAQL SGGQKQRVAI ARALANDPKI LISDEATSAL 
181:	DPKTTKQILA LLQELNRKLG LTIVMITHEM QIVKDICNRV AVMQNGVLIE EGSVLDIFSN 
241:	PKEALTQEFI TTATGIDEAL EKINQQDIVK HLPANALLAQ LKYAGTSTDE PLLNSIYRQF 
301:	EVTANILYGN IEILDHIPVG DMIVVLEGQA ENILAAEKAL HEAGVDVSIL KRGA