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3.A.1.27.2
The chloroplast lipid (trigalactosyl diacyl glycerol (TDG)) transporter, Tdg1,2,3 (Lu et al., 2007). Lipids such as mono- and digalactolipids are synthesized in the endoplasmic reticulum (ER) of plant cells and transferred to the thylakoid membranes of chloroplasts. Mutations in an outer chloroplastic envelope protein with 350 aas and 7 putative TMSs in the last 250 residues may catalyze translocation as part of a lipid transfer complex (Xu et al., 2003; Roston et al. 2012).

Accession Number:Q8L4R0
Protein Name:Tgd1
Length:350
Molecular Weight:37907.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Plastid1 / Multi-pass membrane protein2
Substrate Trigalactosyl diacyl glycerol

Cross database links:

RefSeq: NP_173410.1    NP_973868.1    NP_973869.1   
Entrez Gene ID: 838568   
Pfam: PF02405   
KEGG: ath:AT1G19800   

Gene Ontology

GO:0009706 C:chloroplast inner membrane
GO:0009707 C:chloroplast outer membrane
GO:0016021 C:integral to membrane
GO:0005319 F:lipid transporter activity
GO:0006869 P:lipid transport

References (8)

[1] “A permease-like protein involved in ER to thylakoid lipid transfer in Arabidopsis.”  Xu C.et.al.   12743031
[2] “Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.”  Theologis A.et.al.   11130712
[3] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[4] “Analysis of multiple occurrences of alternative splicing events in Arabidopsis thaliana using novel sequenced full-length cDNAs.”  Iida K.et.al.   19423640
[5] “Mutation of the TGD1 chloroplast envelope protein affects phosphatidate metabolism in Arabidopsis.”  Xu C.et.al.   16199613
[6] “Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.”  Zybailov B.et.al.   18431481
[7] “Lipid trafficking between the endoplasmic reticulum and the plastid in Arabidopsis requires the extraplastidic TGD4 protein.”  Xu C.et.al.   18689504
[8] “Plant ABC proteins - a unified nomenclature and updated inventory.”  Verrier P.J.et.al.   18299247

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MMQTCCIHQS FCFPHRVFPR FDASIGIKPP KLCQVGFIGK TQSYGISSPI RQRRLYVNLN 
61:	ANDGHPSMSM LEEETSTENN APSQEAELPF SKWSPSKYIW RGLSVPIIAG QVVLRILKGK 
121:	IHWRNTLQQL ERTGPKSLGV CLLTSTFVGM AFTIQFVREF TRLGLNRSIG GVLALAFSRE 
181:	LSPVITSIVV AGRMGSAFAA ELGTMQVSEQ TDTLRVLGAD PIDYLITPRV IASCLALPFL 
241:	TLMCFTVGMA SSALLSDAVY GISINIIMDS AHRALRPWDI VSAMIKSQVF GAIISVISCS 
301:	WGVTTTGGAK GVGESTTSAV VMSLVGIFIA DFVLSSFFFQ GAGDSLKNCV