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3.D.13.1.1
The H+ extruding F420 Dehydrogenase (FPO) Complex, FpoABCDFHJKLMNO (see family description for details and Figure 6 in Mand and Metcalf 2019. FpoABCDFHJKLMNO: FpoA, 129 aas, Q8PU58; FpoB, 184 aas, WIM45900.1;  FpoC, 158 aas, WIM42444.1; FpoD, 374 aas, WIM45898.1;  FpoF, 346 aas, WIM47341.1;  FpoH, 350 aas, Q8PU59; FpoJ, 176 aas, Q8FU61; FpoK, 102 aas, F1SVE0; FpoL, 672 aas, WIM45892.1; FpoM, 495 aas, F1SVH9; FpoN, 493 aas, F1SVL2; FpoO 131 aas, AAF65742.1. This is the same system as listed under TC# 3.D.9.1.1.

Accession Number:Q8PU59
Protein Name:F(420)H(2) oxidoreductase subunit H
Length:350
Molecular Weight:38443.00
Species: [2209]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate hydron

Cross database links:

RefSeq: NP_634511.1   
Entrez Gene ID: 1480829   
Pfam: PF00146   
BioCyc: MMAZ192952:MM2487-MONOMER   
KEGG: mma:MM_2487   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0016491 F:oxidoreductase activity
GO:0048038 F:quinone binding
GO:0055114 P:oxidation reduction

References (2)

[1] “The F(420)H(2) dehydrogenase from Methanosarcina mazei is a redox-driven proton pump closely related to NADH dehydrogenases.”  Baeumer S.et.al.   10751389
[2] “The genome of Methanosarcina mazei: evidence for lateral gene transfer between Bacteria and Archaea.”  Deppenmeier U.et.al.   12125824

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MTFMAIEIPE FIVPFVPWIR GTVGLVLVGA IFLGGMAAVW IERKLSADIQ LRYGPSRVGK 
61:	FGLLQLVADA IKLFTKEDVR PGNADRFLYD NAPVFMLTSL FLMLVAIPVG AVFIDGNLYP 
121:	LAVTEMDISI LFIEAVSAIN IFGIFMAAYG SNNKYSLLGA FRNFARMIGY EVPLGIAIVS 
181:	VAVMTGSLNI IDITSAQGSF VWNIFLQPIG FVVFFIALMA DLGRLPFDQN ESEEELVAGW 
241:	VTEYTGMRFG LVFFAEYMHM ILGSFLVALL FLGGWNVPAF VANNAVLGLI APTGILLLKT 
301:	VLVLMTIIGM RWAVPRFRID QVVDMSWKKL LPLSLLNLAW AVGLGLYLGA