3.A.1.33.2
Possible cobalt ion transporter of three subunits, Q8TSC7 (S-subunit, DUF1616, with 550 aas and 8 probable TMSs in a 1 (N-terminus) + 7 (C-terminus) arrangement), Q8TSC8 (A-subunit, ATPase, with 641 aas) and Q8TSC9 (T-subunit, 297 aas, probably with 6 or 7 TMSs). The protein with UniProt acc. # Q8TSC6, encoded adjacent to the three genes encoding the transporter, is CobN, a Co2+/Mg2+ celatase of 1302 aas, and adjacent thereto is a gene encoding a PQQ enzyme of 570 aas with 1 N-terminal TMS.
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| Accession Number: | Q8TSC7 |
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| Protein Name: | DUF1616 domain-containing protein |
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| Length: | 550 |
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| Molecular Weight: | 60981.00 |
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| Species: | Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) [188937] |
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| Number of TMSs: | 8 |
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| Substrate |
magnesium(2+), cobalt(2+) |
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1: MKMSRTGRRR CRKSGKFSNK EKGSRMKNII IFLLVLGLAI QPAAALGQAE DFEPEDMTTF
61: LIQVPHGVEG NGLAVGGSNL SAYVFFESYY EGNMNVTVEL DFPEGFVLQD KTVHSFLLRT
121: EYDDWYRLVD FYVPADLPSG TYNITATALV EVGEKQHTIV RKTRLKVASK EEVAEEIEVS
181: GLTVPSDEDG YGDPSHPAST LVIRETSPAL KKLLKVTDLK IDREELTSTY IGVELSNRGD
241: SKVPVVITYD ILDIKTGEPV KAFKPAIMGM DADTFCYATL TLDPESSSLV SLPLYISENA
301: MGGEYLLRVK VKLTGSDWVA VTKDQKITAI SRKWGPIIIT LVSTLLGLTA TGFFFSRPEQ
361: IMDRFKTRNL VLIALFGTVS FAAINLPMTI LWELSHAIFG PFSFLFTGLF HEVLLYMLIA
421: SLVVLIPKPG VVSLFMLVRF LLGGFITGSF TPITFITMSL SAILLEGLMY AAGITGKNPN
481: PENRFRMGIV CGIADMASGY ASFSVWMVLY RLFYSDWYIM ANILIDGFLY TFIGAWFGIS
541: LGNRLKKVAE