3.A.1.33.2
Possible cobalt ion transporter of three subunits, Q8TSC7 (S-subunit, DUF1616, with 550 aas and 8 probable TMSs in a 1 (N-terminus) + 7 (C-terminus) arrangement), Q8TSC8 (A-subunit, ATPase, with 641 aas) and Q8TSC9 (T-subunit, 297 aas, probably with 6 or 7 TMSs). The protein with UniProt acc. # Q8TSC6, encoded adjacent to the three genes encoding the transporter, is CobN, a Co2+/Mg2+ celatase of 1302 aas, and adjacent thereto is a gene encoding a PQQ enzyme of 570 aas with 1 N-terminal TMS.
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| Accession Number: | Q8TSC9 |
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| Protein Name: | ABC transporter, permease protein |
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| Length: | 297 |
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| Molecular Weight: | 32659.00 |
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| Species: | Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) [188937] |
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| Number of TMSs: | 5 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
magnesium(2+), cobalt(2+) |
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1: MIGARSIAEP TIKDTIIHRM DPRAKILILI STVFVAVTLD NPETMLLLFL IILSGFALAR
61: MPAIKLKTLA ILLTLLIWGT IYSQALFYSQ LPRTVIFTII SPDVPVLGWL TSGGLFVYAE
121: GLHHGAIQGL RSASILSLGL LMCWTTDSRD MLNGLVGLKV PYSAAFMVVT AVRFLPIIIT
181: EVLTVVTVQR LRGFNPKRFG SGIVKTSLNI LTPTLSNCVR RTGTLAVSIQ SRAFRANPDR
241: TYLKKLKFSE FDKAVVAVCI FAAISIVLIK LLYNMYTGGI YYSAGLRPVY ALARGYL