2.A.56.1.11
Tripartite high affinity ectoine/hydroxyectoine uptake system (Grammann et al., 2002). Deletion leads to increased rates of ectoine excretion (Hobmeier et al. 2022). In the absence of the substrate-binding protein, TeaA, an overexpression of both subunits TeaBC facilitated a three-fold increased excretion rate of ectoine export. Individually, the large subunit TeaC showed an approximately five times higher extracellular ectoine concentration per dry weight compared to TeaBC shortly after its expression was induced. This led to the possibility that only the large subunit, TeaC, is required for channel function (Hobmeier et al. 2022).