2.A.6.2.45
The AcrA/AcrB multidrug resistance pump. Exports various toxic compounds, including antibiotics, phytoalexins,
and detergents. Mutants are less virulent on tomato plants than the
wild-type strain (Brown et al. 2007).
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| Accession Number: | Q8Y3H0 |
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| Protein Name: | Putative acriflavin resistance transmembrane protein |
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| Length: | 1049 |
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| Molecular Weight: | 112931.00 |
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| Species: | Ralstonia solanacearum (strain GMI1000) [267608] |
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| Number of TMSs: | 12 |
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| Substrate |
antimicrobial agent, phytoalexin, detergent |
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1: MAKFFIDRPV FAWVLALFII VAGAISITQL PIAQYPTIAP PSIIITATYP GASAKTLDDA
61: VTSIIEQEMN GADGLLYIES VSQAGNGQAT ITVTFKPGTD PALAQVDVQN RLKRVEARLP
121: SSVTQQGVQV DKTRSNFLLF ATLISKDGKM DPVALGDYIS RNVLNEVKRV PGVGQAVLFG
181: TERAMRIWID PAKLVGYKLT PTDVYNAIRN QNALVSAGTL GDLPSTSDQP IAATVVVEGQ
241: MTTTEQFGNI VLVSKPDGSQ VRIKDVARLE LGGQTYATSA RINGQPISAI GVQLSPTGNA
301: LGTAKAVKAK LDELSKYFPA GVEYKIPYDT SKFVQISIEE VVKTLFEAMA LVFLVMLVFL
361: QNIRYTLIPS IVVPISLLGA FATMNALGFS INVLTMFGLV LAIGILVDDA IVVVENVERI
421: MSQEGLPPRE ATRKAMGQIT GAIIGITLVL MAVFIPMAFF SGSVGAIYRQ FSLSMVASIF
481: FSALMALTLT PALCSTLLKP IEKGSHHEKK GFFGWFNRMF TSTTDRYQSL VERVLKKTFR
541: YMVIYGALIA AVVFLFMRLP SSFLPNEDQG YIITNIQLPP AASANRTLEV IKHVENYYQH
601: EKAVENIVAV QGFSFSGNGP NAALVFTTLK DWSSRGADQS ADAVAGRAFG ALFGGIRDAI
661: VFPLNPPPIP ELGNATGFTF RLQDRGGLGH DALMAARNQL LGMAGQSKVL KNVRPDGLED
721: SPQYQVDIDR EKANALGVAF ADINNVLSTA LGSAYANDFP NYGRQQRVIV QADRINRMQP
781: EDIMNLYVRN TQGSMVPMSA FAKGHWVVGP VQLVRYNGYP SVRISGDAAT GASTGDAMDE
841: MEHLASRLPA GIGFEWTGQS LQEKSSGSQA PALYALSLLA VFLVLAALYE SWSIPAAVIL
901: VVPLGVLGAL LGVTLRFMPD DVYFKVGLIA VVGLSAKNAI LIIEFAKDLQ AQGKGLIEAT
961: LEAVHLRFRP IIMTSFAFIL GVLPLAIATG ASSASQRAIG TGVMGGMITA TVLAVVLVPV
1021: FFVVVRRIFK GSERQRRLDA AHLPLDEEI