4.A.6.1.29
Mannose PTS system, IIABCDMan or MpoABCD that transports its sugar substrates slowly and serves as a glucose sensor to regulate the activity of ManR by a phosphorylation/dephosphorylation mechanism. The mannose PTS Enzymes, ManLMN (MptACD), is regulated by ManR. MptACD is the primary
inducible sugar transporting system. ManR is regulated by MpoABCD which transports sugars slowly and serves as a glucose (sugar) sensor
that inactivates the ManR activator by a
phosphorylation/dephosphorylation mechanism (Aké et al. 2011; Zébré et al. 2015).
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| Accession Number: | Q8Y8W1 |
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| Protein Name: | Lmo0781 protein |
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| Length: | 292 |
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| Molecular Weight: | 31781.00 |
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| Species: | Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) [169963] |
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| Number of TMSs: | 4 |
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| Substrate |
glucosamine, glucose, fructose, D-mannopyranose, N-acetyl-beta-D-glucosamine |
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1: MSEQITVNEK KITKSDLMGV FIRSNLFQGS WNFERMQSLG FCFSVIPVIK RLYPEKGPER
61: EQAIKRHLEF FNTHPYMAAP ILGVTTAMEE QKANGADIDD GAINGIKVGL MGPLAGVGDP
121: IFWGTVRPVL AALGAGFATD GSIIGPILFF VLFNAIRLGF RYWGVFYGYT KGTDVVSDMS
181: GGLLQKLTEG ASILGLFVMG ALVNKWTTIY VPLVAYTTED SKTGKDVPTT VQSILDQLMP
241: GLLALLLTFA CMWILKKKVN ALWLILGLFV VGILGYWSGI LGLPPAGYSP LG