3.A.1.114.1
Glycolipid exporter (under nitrogen control in heterocysts), DevABC-HgdD (Moslavac et al., 2007). Heterocyst envelope glycolipids (HGLs) function as an O2 diffusion barrier, being deposited over the heterocyst outer membrane, surrounded by an outermost heterocyst polysaccharide envelope. DevBCA and TolC form an ATP-driven efflux pump required for the export of HGLs across the Gram-negative cell wall (Staron et al., 2011). DevB, the MFP, must be hexameric to create a functional export complex. This system is under NtcA and nitrogen control and is required for heterocyst development (Fiedler et al. 2001).
|
| Accession Number: | Q8YT39 |
|---|
| Protein Name: | HgdD |
|---|
| Length: | 742 |
|---|
| Molecular Weight: | 80838.00 |
|---|
| Species: | Anabaena sp. (strain PCC 7120) [103690] |
|---|
| Location1 / Topology2 / Orientation3: |
Cell outer membrane1 |
|---|
| Substrate |
glycolipid |
|---|
1: MKGQHLFYSF LPGVTAAVLT TQPAVAEAMK VSSVQLVPSS SVVATQNSQT LLVDKSQTQL
61: PNATVQIFPD IIPTSGVTTP NLQFSSSHSH PIILTENTGI DREQKSRQDE VKNFPLKSKL
121: TLSQRLKQRR FSSQQKQINS GITKPKLVTK VVSTTSSTLL AGQQTFSPSY LQNPAPQEKL
181: KTQLPMLLQT KANHVGAAKL LNISSCSPQT CQLTKLTGQQ IAQGNTTQDP ASVPVPDEST
241: LVDTQAPTDT PVPNESAPTD TPVSTESAPA DTQSPRVAPV QTESAPVNTQ APAGAVEVPQ
301: NLIPNANPLQ FPTKPEEVTL KENQPITLTQ ALELARRSNR DLQVSLLELQ RTQALLKEAQ
361: AALLPNLSVS SDVTRSQSAS GQLQDELISK QGGVGNNDEP GTAFNSQAQL SYDLYTSGRR
421: KAAIQEAEEQ VRFNELDVER QSEEIRLSVT RAYYDLQQAD EQVRIARSAV ENAQASLRDA
481: EALERAGVGT RFDVLRSQVN LANNTQQLTN NLSRQQTTRR QLATLLSVPQ AVNISAADPV
541: QLAGLWNQSL EQSIILAYQN RPELHQQLAQ RNISEQQRRQ ALATLGPQVS FVANYNLLDQ
601: FDDGVGLTDG YSVGVRATLN LYDGGAARAR ASQARANIAI AETRFASQRD QVRFQVEQAF
661: TNQRSNLENV QTANVALEQA REALRLARLR FQAGVGTQTD VINSENDLTQ AEGNRITAIL
721: DYNRALAELQ RAVTSRALIS SQ