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3.A.1.12.8 A proline/glycine betaine uptake system. Also reported to be a bile exclusion system that exports oxgall and other bile compounds, BilEA/EB or OpuBA/BB (required for normal virulence) (R.D. Sleator et al., 2005).
Accession Number:	Q93A34
Protein Name:	BilEB aka OpuBB protein
Length:	504
Molecular Weight:	55682.00
Species:	Listeria monocytogenes [1639]
Number of TMSs:	6
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate	Glycine betaine, Proline

Pfam:	PF00528 PF04069
Gene Ontology GO:0016021 C:integral to membrane GO:0005886 C:plasma membrane GO:0005488 F:binding GO:0005215 F:transporter activity GO:0006810 P:transport
References (1) [1] “A PrfA-regulated bile exclusion system (BilE) is a novel virulence factor in Listeria monocytogenes.” Sleator R.D.et.al. 15686563

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FASTA formatted sequence

1:	MNTLIDTFTV RKDELFTALV QHIQISFVSL FIAVLIALPL GIYLTRHKRL AEPIIQVAAI 
61:	FQTIPSLALL GLLIPLVGIG IVPAIIALVI YALLPILRNT YTGIKEVDPA LVEASRAMGM 
121:	NKWKRLYKVQ LPLAMPVIMA GIRTAMVLII GTATLAALIG AGGLGDLILL GIDRNDNSLI 
181:	LLGAIPAALL AILFDFLLRF LEKASFKSTI ITISAGILLT AAIIVVPYFA SDKKEITVAG 
241:	KLGAEPEILI NMYKLVIEDE TDLKVNVKPN MGKTSFVFNA LKSGDIDIYP EFTGTVLETF 
301:	LKENAKTHDP EEVYTQARDG LAKDFDMTYL KPMKYNNTYA LAVSPEFAKE NNLEKISDLG 
361:	PVSDQVKAGF TLEFKDRSDG YKGIQDKYGL TFSNLKTMEP KLRYNAIKSG DINLLDAYST 
421:	DSELAQYKLK VLEDDQQLFP PYQGAPLMLT KTLDKYPELK KPLNKLAGKI TDDEMRKMNY 
481:	EVNVNGKSAY TVAKDYLKDQ GIIK

3.A.1.12.8
A proline/glycine betaine uptake system. Also reported to be a bile exclusion system that exports oxgall and other bile compounds, BilEA/EB or OpuBA/BB (required for normal virulence) (R.D. Sleator et al., 2005).

Cross database links:

Gene Ontology

References (1)

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3.A.1.12.8A proline/glycine betaine uptake system. Also reported to be a bile exclusion system that exports oxgall and other bile compounds, BilEA/EB or OpuBA/BB (required for normal virulence) (R.D. Sleator et al., 2005).

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

3.A.1.12.8
A proline/glycine betaine uptake system. Also reported to be a bile exclusion system that exports oxgall and other bile compounds, BilEA/EB or OpuBA/BB (required for normal virulence) (R.D. Sleator et al., 2005).