3.A.1.5.36
Peptide transporter encoded adjacent to the putative transport system with TC#3.A.1.5.35 (Akanuma et al. 2011). Induced by exogenous S-adenosylmethionine (SAM) at a concentration of 2muM which also enhanced antibiotic production and inhibited morphological development (Park et al. 2005). SAM can be imported into cells. Mutants in the bldK genes confer resistance to the toxic tripeptide, bialaphos (Nodwell et al. 1996).
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| Accession Number: | Q93IU1 |
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| Protein Name: | BldKC, putative ABC transport system integral membrane protein |
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| Length: | 325 |
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| Molecular Weight: | 35607.00 |
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| Species: | Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) [100226] |
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| Number of TMSs: | 6 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
peptide |
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1: MLQFLIRRSF GAVLILVLIS AFTFFMFFAI PQDPAMLACG KNCTPDALEI IHKNLGLDQP
61: VTVQYWHFLA GIFTGRDFAV GHCDAPCFGV SFANNQNVWD TILDRFPLTV SLTVGSLIVF
121: LIVGLGAGLL AAKNRGTWID KVFSSGSLVV SSLQIYFLGP LVLLALVYST GWLQKPKYVP
181: ISEDAAGWFA GLLIPWIVMA TIFTANYTRM SRSSMIEQLQ EEHVRAARAK GMSSNYTFFR
241: YAWRGSLVPI VTILGIDLSA LMGGGMVTEM TFGLAGIGRL ALESVINKDL PMLMGVMLVS
301: AALIIVFNLI VDAMYAVIDP RVRLS