3.A.1.5.36
Peptide transporter encoded adjacent to the putative transport system with TC#3.A.1.5.35 (Akanuma et al. 2011). Induced by exogenous S-adenosylmethionine (SAM) at a concentration of 2muM which also enhanced antibiotic production and inhibited morphological development (Park et al. 2005). SAM can be imported into cells. Mutants in the bldK genes confer resistance to the toxic tripeptide, bialaphos (Nodwell et al. 1996).
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| Accession Number: | Q93IU2 |
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| Protein Name: | BldKB, putative ABC transport system lipoprotein |
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| Length: | 600 |
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| Molecular Weight: | 65533.00 |
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| Species: | Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) [100226] |
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| Number of TMSs: | 1 |
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| Substrate |
peptide |
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1: MSILRNRTAT AAIVAVAAGA LTLTACGGGD SDSSAKDNSK KKEDAKSQSK PVQIGDAQAS
61: TGPAPEVPGA KPGGTMTVYQ TADFSHLDPG QIYVSDGKLL GRLIFRGLTQ YDEDENGNLT
121: VVGDLATDAG KQTDGGKTWT YTLKDNLKDA NGNPINSADI RHTIERMYSS YITDGPTYLQ
181: QWLSGDGTTY RDAYAGPDKG KHLPDNVLET PDDKTIVFHF KTARPDLPQM LTMPGYSVVP
241: EETDTKEKYD SAPVAAGPYK IAEFKPGKSM KLVKNTQWDP KSDSVRHQYV DGFNIEMNHD
301: DEDQTKTLLA DQGGAKNAMM FTGQVATTQL QKVVGDKDAM KNRTIQGYAP YVWQLNFNMN
361: RVKDKKLRDA ITLALPSDSV FKADGGAYGG EVANSLMSPT TPGYDEAFDP FGRAKKPNGD
421: IEAAKKLIKE GGFEGKSLVY AYANTPERQK QAVLISTALE KIGLDIQKKE IDSATWYEQV
481: GKVDNGLDLY MTGWGQDWPS ASTVIPPVYD GKQIQDGASN YSHINDDHVN SEIQRIQQIT
541: DTAEATKAWA ELNEYISKEV NPAAPIYYTK VFQIFGSNVG GIRYSSDSSY VDVTRVFLKK