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2.A.6.2.11 Solvent and antibiotic efflux pump, TtgGHI (SrpABC) (Kieboom et al. 1998; Terán et al., 2007) (solvents extruded include toluene, styrene, m-xylene, ethylbenzene and propylbenzene) (Teran et al., 2007). TtgGHI is the same as SrpABC (Kieboom et al., 1998)
Accession Number:	Q93PU5
Protein Name:	TtgG
Length:	391
Molecular Weight:	42588.00
Species:	Pseudomonas putida [303]
Location¹ / Topology² / Orientation³:	Cell inner membrane¹ / Lipid-anchor²
Substrate	styrene, m-xylene, toluene, ethylbenzene, propylbenzene

Pfam:	PF00529
Gene Ontology GO:0005886 C:plasma membrane GO:0008565 F:protein transporter activity GO:0009306 P:protein secretion
References (2) [1] “Three efflux pumps are required to provide efficient tolerance to toluene in Pseudomonas putida DOT-T1E.” Rojas A.et.al. 11395460 [2] “In vivo and in vitro evidence that TtgV is the specific regulator of the TtgGHI multidrug and solvent efflux pump of Pseudomonas putida.” Rojas A.et.al. 12896994

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MRAERWSQTV RQIRSPRALR VIPLTALMLI SGCGEKEQVS SATPPPDVGV YTVRAQALTL 
61:	TTDLPGRTSA FRVAEVRPQV SGILQKRSFV EGAEVKLGQQ LYQIDPRTYE AQLRRAEANR 
121:	TSAQNLARRY ETLLKTKAVS KQQYDDALAA WKQAEADYQV ARIDVQYTRV LSPISGRIGR 
181:	STVTEGALVT NGQAQSLATV TQLDPIYVDV TQPITKLLGL HKALESGRLQ KTGENQAEVS 
241:	LTLDDGSAYP LPGTLKFSEV SCDPTTGSVT LRAEFPNPNR KLLPGMFVHA LLKEGVQNAA 
301:	ILVPQQAISR DTRGVPSVWV MKADNTVESR EIQTLRTVGN AWLISNGVTE GERIITEGVQ 
361:	RVRSGIAVNA VEAKNVNLVD GFAATTEASA N

2.A.6.2.11
Solvent and antibiotic efflux pump, TtgGHI (SrpABC) (Kieboom et al. 1998; Terán et al., 2007) (solvents extruded include toluene, styrene, m-xylene, ethylbenzene and propylbenzene) (Teran et al., 2007). TtgGHI is the same as SrpABC (Kieboom et al., 1998)

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

2.A.6.2.11Solvent and antibiotic efflux pump, TtgGHI (SrpABC) (Kieboom et al. 1998; Terán et al., 2007) (solvents extruded include toluene, styrene, m-xylene, ethylbenzene and propylbenzene) (Teran et al., 2007). TtgGHI is the same as SrpABC (Kieboom et al., 1998)

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

2.A.6.2.11
Solvent and antibiotic efflux pump, TtgGHI (SrpABC) (Kieboom et al. 1998; Terán et al., 2007) (solvents extruded include toluene, styrene, m-xylene, ethylbenzene and propylbenzene) (Teran et al., 2007). TtgGHI is the same as SrpABC (Kieboom et al., 1998)