Search TCDB: (?)
TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.A.1.5.10
Oligopeptide porter (transports peptides of 4-35) amino acyl residues; di- and tripeptides are not transported; hydrophobic basic peptides are preferred). OppA determines the specificity of the system (Doeven et al., 2004). A large cavity in OppA binds proline-rich peptides preferentially (Berntsson et al., 2009). Two crystal structures of OppA with different nonapeptides show binding in different registers (Berntsson et al., 2011).

Accession Number:Q9CEK0
Protein Name:OppA
Length:600
Molecular Weight:66045.00
Species:Lactococcus lactis subsp. lactis (Streptococcus lactis) [1360]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell membrane1 / Lipid-anchor2
Substrate oligopeptide

Cross database links:

RefSeq: NP_267994.1   
Entrez Gene ID: 1115502   
Pfam: PF00496   
BioCyc: LLAC272623:L88446-MONOMER   
KEGG: lla:L88446   

Gene Ontology

GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0015833 P:peptide transport
GO:0015031 P:protein transport

References (1)

[1] “The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403.”  Bolotin A.et.al.   11337471

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence 
1:	MKKLKVTLLA SSVVLAAALL SACGSNQNSS TSTKKLKAGN FDVAYQNPDK AIKGGNLKIA 
61:	YQSDSPMKAE WLAPLSDDAT FGSMSSPGGG QDGLFFTNSS FKYINGGPAN VSLYKDAKTA 
121:	TITLRKDLKW SDGSEVTAKD YEFSYDLTAN PAYGSDRWTD SLANIVGLSD YHAGKAKTIS 
181:	GITFPDGENG KVIKVQFKEM TPGMNQTGNG YFLETVAPYQ YLKDVAPKDL ASSPKSTTKP 
241:	LVTGPFKPEN VVAGESIKYV PNPYYWGEKP KLNSITYEIV STAKSVAALS AHKYDYINDM 
301:	RASQYKQVKD VKGYKVLGQQ ELYISLMYYN LGHYDVKKSI SVQDRKTPLQ DQNVREALGY 
361:	ARNVAAVQAK FSNGLATPAN GLIPPIFKEF TSPSVKGYEK QDLDKANKLL DEDGWKLNKS 
421:	TGYREKDGKE LSLVYAARVG DANSETIAQN YIQQWKKIGV KVSLYHGKLM EFNSWVDHMT 
481:	TPPGSDDWDI TDGAWSLSGE PSQQDLFSAA APYNFGHFND PEITKDLNDI DSTKAEDSTY 
541:	RKAAFIKYQE DMNKKAYVVP TAYAINYTPV NKRVVGMTLD YGAMNTWSEI GVSSDKMATK