3.A.1.1.42 α-glucoside uptake permease, Agl3E/Agl3F/Agl3G. Plays a role in normal morphogenesis and antibiotic production. Strongly induced by trehalose and melibiose, and weakly induced by lactose and glycerol but not glucose (Hillerich and Westpheling 2006).The operon is controlled by a GntR homologue, Agl3R, and downstream of the gntR gene is a gene encoding an extracellular carbohydrase.
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Accession Number: | Q9FBS6 |
Protein Name: | Putative sugar-transporter integral membrane protein |
Length: | 310 |
Molecular Weight: | 32687.00 |
Species: | Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) [100226] |
Number of TMSs: | 6 |
Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
Substrate |
alpha-glucoside |
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1: MSLSTTSRPA RAVRDLFATA RGRDRLTGLL MTAPAVALFL VMMVVPLVLS GYLSLTDWDG
61: YTAHPAMVGL DHYRALLDDP EVRQAAWITV LLAVIGTLAV NAVGLALALA ISTPGRTNTV
121: LRTVFFYPYV ISALIIGFLW SALLSTNGAV NSVLRAAGHA GLPFLSQPGW ALASLIGVVV
181: WSGFGFTLVL YIAGLHTVPA SLLEAARIDG AGRWRILRSV TLPMIAPVVT VNVVLTLVTL
241: LRSYDLVLSL TGGGPAGSTQ TAAYLILAQS FQNNALGYGS AQSMVLTLVT GIAALAITFL
301: RRRADERAGA