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2.A.6.2.32
Multidrug efflux pump, MexHI OpmD (exports fluoroquinolones; Poole, 2008).  The encoding genes are part of the SoxR regulon (Naseer et al. 2014). These genes are preceded by a gene encoding PA4205, a 148 aas 4 TMS protein, MexG, a member of the DoxX family (TC# 9.B.214) of unknown function, but possibly a component of this ABC transporter (Naseer et al. 2014).

Accession Number:Q9HWH4
Protein Name:MexI
Length:1029
Molecular Weight:111009.00
Species:Pseudomonas aeruginosa GN=mexI PE=4 SV=1 [287]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Host membrane1 / Multi-pass membrane protein2
Substrate fluoroquinolone antibiotic

Cross database links:

RefSeq: NP_252896.1   
Entrez Gene ID: 880346   
Pfam: PF00873   
BioCyc: PAER208964:PA4207-MONOMER   
KEGG: pae:PA4207   

Gene Ontology

GO:0016020 C:membrane
GO:0005215 F:transporter activity
GO:0051301 P:cell division
GO:0006810 P:transport

References (1)

[1] “Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.”  Stover C.K.et.al.   10984043

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTFTDLFVRR PVLALVVSTL ILLLGLFSLG KLPIRQYPLL ESSTITVTTE YPGASADLMQ 
61:	GFVTQPIAQA VSSVEGIDYL SSTSVQGRSV VTIRMLLNRD STQAMTETMA KVNSVRYKLP 
121:	ERAYDSVIER SSGETTAVAY VGFSSKTLPI PALTDYLSRV VEPMFSSIDG VAKVQTFGGQ 
181:	RLAMRLWLDA DRLAGRGLTA SDVAEAIRRN NYQAAPGMVK GQYVLSNVRV NTDLTNVDDF 
241:	REMVIRNDGN GLVRLRDVGT VELGAAATET SALMDGDPAV HLGLFPTPTG NPLVIVDGIR 
301:	KLLPEIQKTL PPDVRVDLAY ETSRFIQASI DEVVRTLVEA LLIVVLVIYL CLGSLRSVLI 
361:	PVATIPLSML GAAALMLAFG FSVNLLTLLA MVLAIGLVVD DAIVVVENVH RHIEEGKSPV 
421:	AAALIGAREV AGPVIAMTIT LAAVYTPIGL MGGLTGALFR EFALTLAGAV IVSGVVALTL 
481:	SPVMSSLLLQ AHQNEGRMGR AAEWFFGGLT RRYGQVLEFS LGHRWLTGGL ALLVCISLPL 
541:	LYSMPKRELA PTEDQAAVLT AIKAPQHANL DYVELFARKL DQVYTSIPET VSTWIINGTD 
601:	GPAASFGGIN LAAWEKRERD ASAIQSELQG KVGDVEGSSI FAFQLAALPG STGGLPVQMV 
661:	LRSPQDYPVL YRTMEEIKQK ARQSGLFVVV DSDLDYNNPV VQVRIDRAKA NSLGIRMQDI 
721:	GESLAVLVGE NYVNRFGMEG RSYDVIPQSL RDQRFTPQAL ARQFVRTQDG NLVPLSTVVR 
781:	VALQVEPNKL IQFDQQNAAT LQAIPAPGVS MGQAVAFLDD VARGLPAGFS HDWQSDSRQY 
841:	TQEGNTLVFA FLAALVVIYL VLAAQYESLA DPLIILITVP LSICGALLPL ALGYATMNIY 
901:	TQIGLVTLIG LISKHGILMV EFANELQLHE RLDRRAAILR AAQIRLRPVL MTTAAMVFGL 
961:	VPLLFASGAG AASRFGLGVV IVSGMLVGTL FTLFVLPTVY TLLARNHAEV DKSPRSRQLA 
1021:	EADLLVNKA