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3.A.1.109.4 The biofilm inducible ABC drug (tobramycin, gentamycin, and ciprofloxacin) resistance pump, PA1875-PA1877 (Zhang and Mah, 2008). It is specifically induced and is most active when growing in a biofilm.
Accession Number:	Q9I2M0
Protein Name:	PA1877
Length:	395
Molecular Weight:	44182.00
Species:	Pseudomonas aeruginosa GN=PA1877 PE=4 SV=1 [287]
Number of TMSs:	1
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate	ciprofloxacin, gentamycin, tobramycin

RefSeq:	NP_250568.1
Entrez Gene ID:	883045
Pfam:	PF00529
BioCyc:	PAER208964:PA1877-MONOMER
KEGG:	pae:PA1877
Gene Ontology GO:0009276 C:Gram-negative-bacterium-type cell wall GO:0016021 C:integral to membrane GO:0008565 F:protein transporter activity GO:0009306 P:protein secretion
References (1) [1] “Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.” Stover C.K.et.al. 10984043

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MDSDRDAAAL RRQLADPLLA ATHPVYRPLL WTLLGCVLLF IGWAAWAQLD EVTRGDGRVV 
61:	PFSRIQKIQS LEGGILDRLL VKEGDLVEVG QPLVRLDETR FLTNFQESAN QASVLRAAIA 
121:	RLDAEVLGKK SIEFPPDVDP EGPLARSERE LFKSRRDKLV EGTQAIQRQI HLAQSQLDLV 
181:	RPLVAKRAVS QMEALKLSQD IATLSGKLTE LKSTYFQDAY TERAQRKADL SALEPIVQQR 
241:	QDQLRRTEIL SPVRGRVNTV LINTRGGVIQ PGEPIMEVIP VEERLLVEAK IKPRDVAFLV 
301:	PGMPAKVKIT AYDYTIYGDL KGTLEQISAD TIEEDTPHGK ESYYQVLIKT DGSQLKRGEE 
361:	VLPIIPGMVA EVDILSGKRS VLNYLLRPLI KARLY

3.A.1.109.4
The biofilm inducible ABC drug (tobramycin, gentamycin, and ciprofloxacin) resistance pump, PA1875-PA1877 (Zhang and Mah, 2008). It is specifically induced and is most active when growing in a biofilm.

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

3.A.1.109.4The biofilm inducible ABC drug (tobramycin, gentamycin, and ciprofloxacin) resistance pump, PA1875-PA1877 (Zhang and Mah, 2008). It is specifically induced and is most active when growing in a biofilm.

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

3.A.1.109.4
The biofilm inducible ABC drug (tobramycin, gentamycin, and ciprofloxacin) resistance pump, PA1875-PA1877 (Zhang and Mah, 2008). It is specifically induced and is most active when growing in a biofilm.