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3.A.1.109.4 The biofilm inducible ABC drug (tobramycin, gentamycin, and ciprofloxacin) resistance pump, PA1875-PA1877 (Zhang and Mah, 2008). It is specifically induced and is most active when growing in a biofilm.
Accession Number:	Q9I2M2
Protein Name:	PA1875
Length:	425
Molecular Weight:	47992.00
Species:	Pseudomonas aeruginosa GN=PA1875 PE=4 SV=1 [287]
Number of TMSs:	1
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate	ciprofloxacin, gentamycin, tobramycin

RefSeq:	NP_250566.1
Entrez Gene ID:	882209
Pfam:	PF02321
BioCyc:	PAER208964:PA1875-MONOMER
KEGG:	pae:PA1875
Gene Ontology GO:0005215 F:transporter activity GO:0006810 P:transport
References (1) [1] “Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.” Stover C.K.et.al. 10984043

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MRGRRQYARK GRRHGKGAIW LLSLGLPMFA SAMPLDQAVR AGLAIHPEVR SAMAEADRAG 
61:	TEVEMAKGGY YPSVTMSGGP QEFDFGEIVY DLTASQMLYD WGRVTSKVDS ASATQRKLSE 
121:	AVLVARDDAA LDIVETYLDV LASERRVEAV REHIQRLDGI REMTQARGGD GYADRSELDR 
181:	ANLELSRAQE QLSLEKGNLQ DARNQYAILV GQEPADLVEP EPMSLQRYLA ASDMARVIRE 
241:	SPLQRKALED ANVAEAEVRE AKASLLPQLN LEASALRREI GGHPESDSVV SLRFRMDTFQ 
301:	GLSNFRRPTA AQQRLESAKW SADAMQRDIR RQLQNLFDNG DTLRWREQSL TQQVTESEQV 
361:	GELYREQFEV GRRDVIDLLN VQRERFEAER QLINLRIERK RIEYRAAAQV GLLGPLLENR 
421:	LNHGS

3.A.1.109.4
The biofilm inducible ABC drug (tobramycin, gentamycin, and ciprofloxacin) resistance pump, PA1875-PA1877 (Zhang and Mah, 2008). It is specifically induced and is most active when growing in a biofilm.

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

3.A.1.109.4The biofilm inducible ABC drug (tobramycin, gentamycin, and ciprofloxacin) resistance pump, PA1875-PA1877 (Zhang and Mah, 2008). It is specifically induced and is most active when growing in a biofilm.

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

3.A.1.109.4
The biofilm inducible ABC drug (tobramycin, gentamycin, and ciprofloxacin) resistance pump, PA1875-PA1877 (Zhang and Mah, 2008). It is specifically induced and is most active when growing in a biofilm.