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3.A.1.12.6
Uptake system for hisitidine, proline, proline-betaine and glycine-betaine

Accession Number:Q9KKE1
Protein Name:HutV aka HISV aka R02702 aka SMC00670
Length:275
Molecular Weight:30364.00
Species:Rhizobium meliloti (Sinorhizobium meliloti) [382]
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Histidine, Proline, Proline betaine, Glycine betaine

Cross database links:

HEGENOM: HBG758042
RefSeq: NP_386808.1   
Entrez Gene ID: 1234377   
Pfam: PF00005   
BioCyc: SMEL266834:SMC00670-MONOMER   
KEGG: sme:SMc00670   

Gene Ontology

GO:0005524 F:ATP binding
GO:0016887 F:ATPase activity

References (2)

[1] “Characterization of a Snorhizobium meliloti ATP-binding cassette histidine transporter also involved in betaine and proline uptake.”  Boncompagni E.et.al.   10850986
[2] “Analysis of the chromosome sequence of the legume symbiont Sinorhizobium meliloti strain 1021.”  Capela D.et.al.   11481430

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MADIEIRNVY KIFGHDAKKA LTMVEDGLDK ADILSRSGCT VGLNDVSLKI GAGKIFVIMG 
61:	LSGSGKSTLV RHINRLIEPT SGEVLFDGDN ILDLGAKALR AFRMRRVSMV FQSFALMPHR 
121:	TVLQNVVYGQ RVRGVSKDDA REIGMKWIDT VGLSGYDAKF PHQLSGGMKQ RVGLARALAA 
181:	DTDVILMDEA FSALDPLIRG DMQDQLLQLQ RNLAKTIVFI THDLDEALRI GSEIAILRDG 
241:	QVVQVGTPND ILDNPANDYV ARFVQRRHER PQTHG