TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.C.131.1.1
A secreted lipid binding protein of 1085 aas and 5 - 6 TMSs, VasX.  Essential for killing of Dictyostelium discoideum (Miyata et al. 2011).  It is a pore-forming toxin (Durand et al. 2014). It is a T6SS effector and may have a structure resembling that of Colicin Ia (Russell et al. 2014). VasW (295 aas, possibly with a C-terminal TMS) is an accessory protein for VasX (Miyata et al. 2013). The TsiV2 immunity protein (242 aas and 3 or 4 TMSs) protects against VasX. Its gene is adjacent to the vasX gene, and its promoter is within the vasX gene, clearly suggesting a common functional role to counteract the function of VasX (Miyata et al. 2013).

Accession Number:Q9KNE6
Protein Name:Accessory protein VasW
Length:295
Molecular Weight:34214.00
Species:Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) [243277]
Substrate

Cross database links:

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MRSTNSFVVH NWVSLVPEME MDTQERLYLL VDGAQISHLA QALYRLSGEL VLEPLYLFPP 
61:	FEQLKEVSPY LVLATDTVKT WFLEQNQGLA GFFFASLDSI EEIAEQLRRL IQVESPYGST 
121:	VFLKMANSEC AYVLLSTQCQ PLWKVINRAW LPTRQGWQYV QRPELTATQD TPVRFKLTDE 
181:	QWQRLGNITW LNTLETVERH VQQWFPDLAQ QWQSDPELFH RHAQWAYQQG FSSERDLMLF 
241:	FNVLGFLGVD ALEKGKYPEI DPLLHQASSR TPSQRIEAAA ELAYQHSQSS QEVQG