3.A.16.1.5
The ER-associated degradation (ERAD) pathway of 47 proteins (Liu and Li 2014).
|
| Accession Number: | Q9LW77 |
|---|
| Protein Name: | ERAD-associated E3 ubiquitin-protein ligase HRD1A |
|---|
| Length: | 492 |
|---|
| Molecular Weight: | 56037.00 |
|---|
| Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
|---|
| Number of TMSs: | 6 |
|---|
| Location1 / Topology2 / Orientation3: |
Endoplasmic reticulum membrane1 / Multi-pass membrane protein2 |
|---|
| Substrate |
protein |
|---|
1: MIRLRTYAGL SFMATLAVIY HAFSSRGQFY PATVYLSTSK ISLVLLLNMC LVLMLSLWHL
61: VKFVFLGSLR EAEVERLNEQ AWRELMEILF AITIFRQDFS SGFLPLVVTL LLIKALHWLA
121: QKRVEYIETT PSVSKLSHFR IVSFMGFLLL VDSLFMYSSI RHLIQSRQAS VSLFFSFEYM
181: ILATTTVAIF VKYVFYVTDM LMDGQWEKKP VYTFYLELIR DLLHLSMYIC FFFVIFMNYG
241: VPLHLLRELY ETFRNFQIRV SDYLRYRKIT SNMNDRFPDA TPEELTASDA TCIICREEMT
301: NAKKLICGHL FHVHCLRSWL ERQQTCPTCR ALVVPPENAT SAAPGQRELH QGSQQGTSSS
361: GNQGSEISSS AGVSNNSLSR HHARLQAAAS AASVYGKSMV YPSANTVAWS SGVPGTEQVS
421: TEPDQTLPQH NLPVENSHAY ANMSETKLEE MRKSLETHLE ILRNRLHFLE TRKPESAGEP
481: ENKGKSVADA AE