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3.A.7.15.1
The nonspecific tight adherence fibril (pilus) secretion septum (Flp-1, Flp-2, TadV-RcpCAB Tad ZA-G) (Kachlany et al., 2000; Bhattacharjee et al., 2001; Haase et al., 2003; Schreiner et al., 2003; Wang and Chen, 2005; Tomich et al. 2007). The outer membrane components of the Tad (tight adherence) secreton have been identified (Clock et al. 2008). The tad locus is required for tenacious, nonspecific adherence to surfaces and formation of extremely strong biofilms. This locus is dedicated to the biogenesis of Flp pili, which are required for colonization and virulence (Perez et al. 2006).

Accession Number:Q9S4A4
Protein Name:TadG
Length:538
Molecular Weight:60412.00
Species: [714]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate protein polypeptide chain

Cross database links:

References (3)

[1] “Nonspecific adherence by Actinobacillus actinomycetemcomitans requires genes widespread in bacteria and archaea.”  Kachlany S.C.et.al.   11029439
[2] “Genes for tight adherence of Actinobacillus actinomycetemcomitans: from plaque to plague to pond scum.”  Kachlany S.C.et.al.   11553455
[3] “The Widespread Colonization Island of Actinobacillus actinomycetemcomitans.”  Planet P.J.et.al.   12717435

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MKRNFNLTAK LFSTVKQFLQ NEHGVYTIIT ALLAFPLLLF VAFTVDGTGI LLDKARLAQA 
61:	TDQAALLLIA EDNQYRKNKD HSDVTRQRVS QQDIDRESKD FSNAKVQAQW KKRNQELVQG 
121:	LVKLYLRSDD SNGQKNSSPV TIKEPFLAEC LEEKTQPRNK NGTAKSIACV VQGSVQRKFW 
181:	LPWGQTLVSS SQLHDGRVGI NSGETYAVKE KQITIPIDLM MVTDLSRSMN WAIVSHRDVE 
241:	VPPPNRRIDA LREVVSNIQD ILLPKAIRDD ISPYNRIGFV SFAAGARQKD ETDNCVLPYY 
301:	SKQNKQAEIS NYFNSGQISQ GFEELSRSMD IEKTINQITQ FKNGEKKSYP FSLSSLSSRN 
361:	FCLENNKGKA TTQAWFSKSK PGVADALKEI EPLGGTAVTS GIFIGTNLMT DTNKDPEAAP 
421:	NKLNTNTRRV LLILSDGEDN RPSKNTLVTF MNSGMCEKIK EKINSLQDSN YPQVEARIAF 
481:	VALGFNPPQD QLIAWKKCVG KQYYPVNSKQ GLLDAFKQII SFEEEVGRSS SQKPKLFQ