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3.A.7.15.1
The nonspecific tight adherence fibril (pilus) secretion septum (Flp-1, Flp-2, TadV-RcpCAB Tad ZA-G) (Kachlany et al., 2000; Bhattacharjee et al., 2001; Haase et al., 2003; Schreiner et al., 2003; Wang and Chen, 2005; Tomich et al. 2007). The outer membrane components of the Tad (tight adherence) secreton have been identified (Clock et al. 2008). The tad locus is required for tenacious, nonspecific adherence to surfaces and formation of extremely strong biofilms. This locus is dedicated to the biogenesis of Flp pili, which are required for colonization and virulence (Perez et al. 2006).

Accession Number:Q9S4A5
Protein Name:TadF
Length:200
Molecular Weight:22925.00
Species:Actinobacillus actinomycetemcomitans (Haemophilus actinomycetemcomitans) [714]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate protein polypeptide chain

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References (3)

[1] “Nonspecific adherence by Actinobacillus actinomycetemcomitans requires genes widespread in bacteria and archaea.”  Kachlany S.C.et.al.   11029439
[2] “Genes for tight adherence of Actinobacillus actinomycetemcomitans: from plaque to plague to pond scum.”  Kachlany S.C.et.al.   11553455
[3] “The Widespread Colonization Island of Actinobacillus actinomycetemcomitans.”  Planet P.J.et.al.   12717435

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MANHWYKNMK KNILTNTKKF FHNKRGAVSL EFLFMLILLV FIFAFLTDLV IVRTTQGKLD 
61:	NASYSLVNVL RERNQLYNDN GSKPLKSTDL TEYEKMAKLI LFGDKDSPNK VGVTIEHWEE 
121:	KKSPESLTTL STCQPYRKLD NNLSYLSPRS EAANPDNQRK IPLYQVTLCV EAGSFFKNLI 
181:	TRKENQSFGM LSSSSLAVAR