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3.A.7.15.1
The nonspecific tight adherence fibril (pilus) secretion septum (Flp-1, Flp-2, TadV-RcpCAB Tad ZA-G) (Kachlany et al., 2000; Bhattacharjee et al., 2001; Haase et al., 2003; Schreiner et al., 2003; Wang and Chen, 2005; Tomich et al. 2007). The outer membrane components of the Tad (tight adherence) secreton have been identified (Clock et al. 2008). The tad locus is required for tenacious, nonspecific adherence to surfaces and formation of extremely strong biofilms. This locus is dedicated to the biogenesis of Flp pili, which are required for colonization and virulence (Perez et al. 2006).

Accession Number:Q9S4A6
Protein Name:TadE
Length:191
Molecular Weight:21657.00
Species:Actinobacillus actinomycetemcomitans (Haemophilus actinomycetemcomitans) [714]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate protein polypeptide chain

Cross database links:

Pfam: PF07811   

References (3)

[1] “Nonspecific adherence by Actinobacillus actinomycetemcomitans requires genes widespread in bacteria and archaea.”  Kachlany S.C.et.al.   11029439
[2] “Genes for tight adherence of Actinobacillus actinomycetemcomitans: from plaque to plague to pond scum.”  Kachlany S.C.et.al.   11553455
[3] “The Widespread Colonization Island of Actinobacillus actinomycetemcomitans.”  Planet P.J.et.al.   12717435

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MKKFLSNKKG ASTVEFALTV VFYFFVVFLI LEFCRISITT AYWDLAITES ARIAKNRTAE 
61:	GNDYAVEFEK ALKQQLVYQE SSTLGYLARL DKNGGYKIDV KYVDCGSESS CVKSLLDGRF 
121:	RQPTKDRDGK IIPPNGRLAT LAVYSLTYNY EFLVSLPFLP KDSVGGLLSR KFVAVQEFNR 
181:	SKFQYPGRSN K