1.A.130.1.1
Nortia (Nta), the Ca2+ channel protein of 895 aas and ~ 10 TMSs in a 1 + 1 + 2 + 6 [2 + 2 + 2) TMS arrangement (O22752); Feronia (Fer) a receptor-like kinase and constituent of a transmembrane calmodulin-gated calcium (Ca2+) channel protein complexof 542 aas, an MLO-like protein, and Lorleei (Lre, glycosyl PI anchor protein of 165 aas with 2 TMSs, one N-terminal and one C-terminal (B3GS44) (Gao et al. 2022). The channel protein (Nortia) functions in conjunction with these two other proteins, Feronia (Fer), a receptor-like protein kinase, and Lorelei (Lre), a GPI-anchored protein. See the family description, paragraph 1 and Gao et al. 2022 for more details. Two pollen-tube-derived small peptides that belong to the rapid alkalinzation factor (RALF) family seem to be ligands for the FER-LRE co-receptor, which in turn recruits NTA to the plasm membrane. NTA initiates Ca2+ spiking in the synergid cells, for pollen tube reception. Thus, the FER-LRE-NTA complex forms a receptor-channel complex in the female cell to recognize male signals and trigger tertilization.
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| Accession Number: | Q9SCZ4 |
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| Protein Name: | Receptor-like protein kinase FERONIA |
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| Length: | 895 |
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| Molecular Weight: | 98150.00 |
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| Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
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| Number of TMSs: | 3 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Single-pass type I membrane protein2 |
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| Substrate |
calcium(2+) |
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1: MKITEGRFRL SLLLLLLLIS AATLISAADY SPTEKILLNC GGGASNLTDT DNRIWISDVK
61: SKFLSSSSED SKTSPALTQD PSVPEVPYMT ARVFRSPFTY TFPVASGRKF VRLYFYPNSY
121: DGLNATNSLF SVSFGPYTLL KNFSASQTAE ALTYAFIIKE FVVNVEGGTL NMTFTPESAP
181: SNAYAFVNGI EVTSMPDMYS STDGTLTMVG SSGSVTIDNS TALENVYRLN VGGNDISPSA
241: DTGLYRSWYD DQPYIFGAGL GIPETADPNM TIKYPTGTPT YVAPVDVYST ARSMGPTAQI
301: NLNYNLTWIF SIDSGFTYLV RLHFCEVSSN ITKINQRVFT IYLNNQTAEP EADVIAWTSS
361: NGVPFHKDYV VNPPEGNGQQ DLWLALHPNP VNKPEYYDSL LNGVEIFKMN TSDGNLAGTN
421: PIPGPQVTAD PSKVLRPTTR KSKSNTAIIA GAASGAVVLA LIIGFCVFGA YRRRKRGDYQ
481: PASDATSGWL PLSLYGNSHS AGSAKTNTTG SYASSLPSNL CRHFSFAEIK AATKNFDESR
541: VLGVGGFGKV YRGEIDGGTT KVAIKRGNPM SEQGVHEFQT EIEMLSKLRH RHLVSLIGYC
601: EENCEMILVY DYMAHGTMRE HLYKTQNPSL PWKQRLEICI GAARGLHYLH TGAKHTIIHR
661: DVKTTNILLD EKWVAKVSDF GLSKTGPTLD HTHVSTVVKG SFGYLDPEYF RRQQLTEKSD
721: VYSFGVVLFE ALCARPALNP TLAKEQVSLA EWAPYCYKKG MLDQIVDPYL KGKITPECFK
781: KFAETAMKCV LDQGIERPSM GDVLWNLEFA LQLQESAEEN GKGVCGDMDM DEIKYDDGNC
841: KGKNDKSSDV YEGNVTDSRS SGIDMSIGGR SLASEDSDGL TPSAVFSQIM NPKGR