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3.A.7.15.1
The nonspecific tight adherence fibril (pilus) secretion septum (Flp-1, Flp-2, TadV-RcpCAB Tad ZA-G) (Kachlany et al., 2000; Bhattacharjee et al., 2001; Haase et al., 2003; Schreiner et al., 2003; Wang and Chen, 2005; Tomich et al. 2007). The outer membrane components of the Tad (tight adherence) secreton have been identified (Clock et al. 2008). The tad locus is required for tenacious, nonspecific adherence to surfaces and formation of extremely strong biofilms. This locus is dedicated to the biogenesis of Flp pili, which are required for colonization and virulence (Perez et al. 2006).

Accession Number:Q9XC05
Protein Name:TadB
Length:295
Molecular Weight:34345.00
Species:Actinobacillus actinomycetemcomitans (Haemophilus actinomycetemcomitans) [714]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate protein polypeptide chain

Cross database links:

Pfam: PF00482   

References (3)

[1] “Nonspecific adherence by Actinobacillus actinomycetemcomitans requires genes widespread in bacteria and archaea.”  Kachlany S.C.et.al.   11029439
[2] “Genes for tight adherence of Actinobacillus actinomycetemcomitans: from plaque to plague to pond scum.”  Kachlany S.C.et.al.   11553455
[3] “The Widespread Colonization Island of Actinobacillus actinomycetemcomitans.”  Planet P.J.et.al.   12717435

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MNYYLYYAVL TIGGLLFIYT LSSWFSTKRK INEYDTSVSR TTSFFKSLKS KISLWYYHFT 
61:	KGDKRNLIRN IVISCFILFA FFVINVAYIH IDRLVFCLIF LVGFVLFIWK LGQYRNKKTF 
121:	NAMFPEVIQI LNAAATSGAG LLQALERCGK DLTGQLGEEF KSIHKRIAIG EDPVSVFEDS 
181:	YDRYPYKEFY FFITIVRTNL SKGGQIREVI SRLGRVIADS NKMEKKKKAM TSEARMSAII 
241:	VACFPVGFFF FMQFAMPENF DFLINDPTGR YVLYYVFGSE LFGMGIIWWL MRKST