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3.A.7.15.1
The nonspecific tight adherence fibril (pilus) secretion septum (Flp-1, Flp-2, TadV-RcpCAB Tad ZA-G) (Kachlany et al., 2000; Bhattacharjee et al., 2001; Haase et al., 2003; Schreiner et al., 2003; Wang and Chen, 2005; Tomich et al. 2007). The outer membrane components of the Tad (tight adherence) secreton have been identified (Clock et al. 2008). The tad locus is required for tenacious, nonspecific adherence to surfaces and formation of extremely strong biofilms. This locus is dedicated to the biogenesis of Flp pili, which are required for colonization and virulence (Perez et al. 2006).

Accession Number:Q9XC06
Protein Name:TadA
Length:426
Molecular Weight:47140.00
Species:Actinobacillus actinomycetemcomitans (Haemophilus actinomycetemcomitans) [714]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate protein polypeptide chain

Cross database links:

Pfam: PF00437   

Gene Ontology

GO:0005622 C:intracellular
GO:0005524 F:ATP binding
GO:0006810 P:transport

References (3)

[1] “Nonspecific adherence by Actinobacillus actinomycetemcomitans requires genes widespread in bacteria and archaea.”  Kachlany S.C.et.al.   11029439
[2] “Genes for tight adherence of Actinobacillus actinomycetemcomitans: from plaque to plague to pond scum.”  Kachlany S.C.et.al.   11553455
[3] “The Widespread Colonization Island of Actinobacillus actinomycetemcomitans.”  Planet P.J.et.al.   12717435

External Searches:

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MLTKQQKILL RSEVLSNLDI EKIDELQSER SSLVNELVQI VNRVANKSGA YLTSADTLVM 
61:	AEIVADEIEG YGPLRDLMAD DTINDILVNG PNDIWVERAG ILEKTDKEFV SNEQLTDIAK 
121:	RLVARVGRRI DDGSPLVDSR LPDGSRLNVV IAPIALDGTS ISIRKFSKNK KTLQELVNFG 
181:	SMTREMANFL IIAARSRVNI IVSGGTGSGK TTLLNALSNY ISHTERVITL EDTAELRLEQ 
241:	PHVVRLETRL AGVEHTGEVT MQDLVINALR MRPERIIVGE CRGGEAFQML QAMNTGHDGS 
301:	MSTLHANSPR DATSRLESMV MMSNASLPLE AIRRNISSAV NIIVQASRLN DGSRKIMNIT 
361:	EVMGMENGQI VLQDMFSYKA SKYRDKEGKI LGEFINHGLL TRSIVFQNAQ VFNLSAELQS 
421:	IFGETE