2.A.6.2.33
Multidrug efflux pump, MexVW-OprM (exports fluoroquinolones, macrolides, chloramphenicol, tetracycline, erythromycin, ethidium bromide and acriflavine, and elevated ethidium bromide extrusion was observed (Li et al. 2003). MexAB-OprM and MexVW-OprM were both expressed at increased levels in the presence of elevated Ca2+ (Khanam et al. 2017).
|
| Accession Number: | QKK87500.1 |
|---|
| Protein Name: | QKK87500.1 multidrug efflux RND transporter periplasmic adaptor subunit MexV [Pseudomonas aeruginosa] |
|---|
| Length: | 377 |
|---|
| Molecular Weight: | |
|---|
| Species: | Pseudomonas aeruginosa [287] |
|---|
| Number of TMSs: | 1 |
|---|
| Substrate |
macrolide, fluoroquinolone antibiotic, chloramphenicol, tetracycline, erythromycin A, 3,6-diamino-10-methylacridinium chloride, ethidium bromide |
|---|
1: MLLRRMLIML AAVIAVVAIL AGYKVYSIRQ QIALFSAPKP PISVTASLAE KRPWQSRLPA
61: IGSLKAFQGV TLTAEVSGTV RDVLFLSGDQ VKLDQPLIQL ESDVEEATLR TAEADLGLAR
121: AEYQRGRELI GSKAISKSEF DRLAAQWAKT SATVAELKAA LAKKRVLAPF AGTIGIRQVD
181: VGDYVSPGTP IATLQDLSTL LLDFHLPEQD FPLLSRGQLV KVRVAAYPAQ VFDAEIAAIN
241: PKVDNETRNL QVRAALENPD GKLLPGMFAN LEVMLPGEEQ RVVVPETAIT FTLYGDSIYV
301: VGQKKDEQGQ VSKDDKGQPQ QVVERRFVRI GERREGLAVV LEGLEGGEQV VTSGQLKLDN
361: GAAVAIVAER DLQQEH