9.A.12.1.1
Putative lantibiotic (NAI-107) immunity exporter, MlbJ (247 aas; 6 TMSs)/Q (lipoprotein of 141 aas). Distinct immunity
determinants are: the ABC transporter MlbYZ, and acting cooperatively,
the transmembrane protein, MlbJ, and the lipoprotein, MlbQ. NMR
structural analysis of MlbQ revealed a hydrophobic surface patch which was proposed to bind the cognate lantibiotic (Pozzi et al. 2015).
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| Accession Number: | W2EQW9 |
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| Protein Name: | Uncharacterized protein |
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| Length: | 247 |
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| Molecular Weight: | 24831.00 |
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| Species: | Microbispora sp. ATCC PTA-5024 [316330] |
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| Number of TMSs: | 6 |
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| Substrate |
lantibiotic |
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1: MVAQGVPVEG AGRHAGGQAI GDALNRSGVF CYSPGVEMVS VELWRHEVRR CGLVALVTPL
61: AVVASTTLLS ALAGGGMHDF LAVWLPAALL PLVAGVCAVG VVSREVMPEL QATFPTPYPV
121: TVRRRLRLLI LAVGAGVVVL AVSAATGAGH DPVTGQGASG PVLSSLFSAA SSAAFSLLLI
181: GVGAYAAAGR TRNRGGPASA LVMTAWLAKL LVLDRIPLPP AAVAVAFAAA GLWSMVRGST
241: RAGGEAV