1.A.1.11.34
Calcium channel of 913 aas and 12 TMSs. Ca2+ channels in trophozoites are inhibited by Amlodipine (Baig et al. 2013).
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| Accession Number: | L8H0U0 |
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| Protein Name: | Transporter, cation channel family protein |
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| Length: | 913 |
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| Molecular Weight: | 104980.00 |
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| Species: | Acanthamoeba castellanii str. Neff [1257118] |
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| Number of TMSs: | 12 |
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| Substrate |
calcium ion |
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1: MSETERILSI NAIDELEDED EGQGMTQFPP TPGCPGTYDD EVDPQALLIA ATFVSDAIYG
61: RLEEHRTDMG SLRLYRAYKR GWVQLSWKLF IYVDLFLAFI EPPYTITPPF DGLSAVLEVI
121: CMIALLAELV VRFQFLERRA FFRSPKIITQ ILVITATLAD VMLSSATGNT LRLTRYLRPW
181: WLFYSSRLLR TATNTIRRIV FSLFDLLLLI LLAIILFGSV CAVIFAGSHE GREYFPDLFT
241: AYINLYFGLY SLNYPDIMIP AYHASAWWSL LFIGYVLVVS WFLMAIVLAT IYTVYKSGLK
301: GEVAQVLYHQ HQRLAAAWQL FGCHVSGKLS WPVWEQLFAV LKPHYRPEKV AMVFRILDKG
361: QKGYLRYKEF LRIVDLLTYR LHRINVSPHV FGRAWPSLYY SRASKVFRKI VLHKFASWAV
421: DFVIVVSVVV LLVELQLQLN GDNITTEVRF ENHASEYVLF SVLWLEFFCR VYALGPSAYW
481: RYHWHKFDVL LLAFVSLGFS ILLADFNTPI DWVKVIFIGR LLRLTRLFSR VLYYVFALIG
541: MQIWAGKITK DTAALKGTTF ADLGYYMLNF NSFLEALFTL FHLNVINNYN VTAVGYSAVS
601: GKAAWLFFVI FNLLAVIVLF NVMVAFIIEA FQKRQQKANT QDPMLKRIRK ITLKVEGAAG
661: GLYAWQAEDS RDPFHILRRL LLDEILEEDE VYSWLNYVEE HHGTDKEKKA DGKEHKKRSR
721: HHSDTESEDE GEHADIKNAI NNLGGLPNNS TISPAPTSIT GWHLPEDQGS SRRLRVSSTL
781: PRGICRGGTI YIPNRTREDH PGASSAFASW DNAAAFEGED EEELGGAAGQ EQLFGRPRRQ
841: GVGEIGGKIR HAWLRQWRGK GTDNRFYIPR ITRDRANNLR VVWEDEDEEY DEHLQEREEN
901: RQRRRGNGGN QDA