1.A.1.5.23
Cyclic nuceotide-gated Na+ channel of 729 aas and 6 putative TMSs, CNGC19. It is constitutively expressed in roots but induced in leaves and shoots under conditions of salt (NaCl) stress (Kugler et al. 2009). CNG19 and CNGC20 self-associate, form heteromeric complexes, and these complexes arei phosphorylated and stabilized by BOTRYTIS INDUCED KINASE1 (BIK1). Tight
control of the CNG19/CNGC20 Ca2+ ion channel is important for regulating immunity (Zhao et al. 2021).
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| Accession Number: | Q9LDR2 |
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| Protein Name: | Putative cyclic nucleotide-gated ion channel 19 |
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| Length: | 729 |
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| Molecular Weight: | 84049.00 |
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| Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
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| Number of TMSs: | 7 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
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| Substrate |
sodium(1+) |
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1: MAHTRTFTSR NRSVSLSNPS FSIDGFDNST VTLGYTGPLR TQRIRPPLVQ MSGPIHSTRR
61: TEPLFSPSPQ ESPDSSSTVD VPPEDDFVFK NANLLRSGQL GMCNDPYCTT CPSYYNRQAA
121: QLHTSRVSAS RFRTVLYGDA RGWAKRFASS VRRCLPGIMN PHSKFVQVWT RVLAFSSLVA
181: IFIDPLFFFL LLIQQDNKCI AIDWRATKVL VSLRSITDLI FFINILLQFR LAYVAPESRI
241: VGAGQLVDHP RKIARHYFRG KFLLDMFIVF PIPQIMILRI IPLHLGTRRE ESEKQILRAT
301: VLFQYIPKLY RLLPLLAGQT STGFIFESAW ANFVINLLTF MLAGHAVGSC WYLSALQRVK
361: KCMLNAWNIS ADERRNLIDC ARGSYASKSQ RDLWRDNASV NACFQENGYT YGIYLKAVNL
421: TNESSFFTRF SYSLYWGFQQ ISTLAGNLSP SYSVGEVFFT MGIIGLGLLL FARLIGNMHN
481: FLQSLDRRRM EMMLRKRDVE QWMSHRRLPE DIRKRVREVE RYTWAATRGV NEELLFENMP
541: DDLQRDIRRH LFKFLKKVRI FSLMDESVLD SIRERLKQRT YIRSSTVLHH RGLVEKMVFI
601: VRGEMESIGE DGSVLPLSEG DVCGEELLTW CLSSINPDGT RIKMPPKGLV SNRNVRCVTN
661: VEAFSLSVAD LEDVTSLFSR FLRSHRVQGA IRYESPYWRL RAAMQIQVAW RYRKRQLQRL
721: NTAHSNSNR