1.A.1.5.27
CNGC15 of 678 aas and 6 TMSs. In Medicago truncatula, three such channels, CNGC15a, b and c, are required for nuclear calcium oscillations, spiking and subsequent symbiotic responses. These three channels form a complex with the potassium permeable channel, DMI1 (TC# 1.A.1.23.1), in the nuclear envelope. They are expressed in flowers and pods, and mutants in these channels have decreased fertilization rates (Charpentier et al. 2016).
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| Accession Number: | Q9SL29 |
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| Protein Name: | Putative cyclic nucleotide-gated ion channel 15 |
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| Length: | 678 |
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| Molecular Weight: | 78723.00 |
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| Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
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| Number of TMSs: | 7 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
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| Substrate |
calcium(2+) |
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1: MGYGNSRSVR FQEDQEVVHG GESGVKLKFK INGTQINNVK MMSKGKFLKA KVLSRVFSED
61: LERVKTKILD PRGQTIRRWN KIFLIACLVS LFVDPLFFFL PVMRNEACIT IGVRLEVVLT
121: LIRSLADAFY IAQILIRFRT AYIAPPSRVF GRGELVIDSR KIAWRYLHKS FWIHLVAALP
181: LPQVLIWIII PNLRGSPMTN TKNVLRFIII FQYVPRMFLI FPLSRQIIKA TGVVTETAWA
241: GAAYNLMLYM LASHVLGACW YLLAVERQEA CWRHACNIEK QICQYRFFEC RRLEDPQRNS
301: WFEWSNITTI CKPASKFYEF GIFGDAVTST VTSSKFINKY FYCLWWGLKN LSSLGQNLAT
361: STYAGEILFA IIIATLGLVL FALLIGNMQT YLQSTTMRLE EWRIRRTDTE QWMHHRQLPP
421: ELRQAVRKYD QYKWLATRGV DEEALLISLP LDLRRDIKRH LCFDLVRRVP LFDQMDERML
481: DAICERLKPA LCTEGTFLVR EGDPVNEMLF IIRGHLDSYT TNGGRTGFFN SCLIGPGDFC
541: GEELLTWALD PRPVVILPSS TRTVKAICEV EAFALKAEDL QFVASQFRRL HTKQLRHKFR
601: FYSHQWRTWA ACFIQAAWRR HRKRKYKTEL RAKEEFHYRF EAATARLAVN GGKYTRSGSD
661: SGMMSSIQKP VEPDFSSE