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1.A.1.7.5 Two-pore potassium channel 5 (AtTPK5) (Calcium-activated outward-rectifying potassium channel 5, chloroplastic) (AtKCO5). Reviewed by González et al. 2014.
Accession Number:	Q9S6Z8
Protein Name:	Two-pore potassium channel 5
Length:	408
Molecular Weight:	46259.00
Species:	Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:	4
Location¹ / Topology² / Orientation³:	Vacuole membrane¹ / Multi-pass membrane protein²
Substrate	potassium(1+)

Entrez Gene ID:	828091
Pfam:	PF07885
KEGG:	ath:AT4G01840
Gene Ontology GO:0016021 C:integral to membrane GO:0009705 C:plant-type vacuole membrane GO:0005267 F:potassium channel activity
References (5) [1] “Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.” Mayer K.F.X.et.al. 10617198 [2] “Phylogenetic relationships within cation transporter families of Arabidopsis.” Maeser P.et.al. 11500563 [3] “AtTPK4, an Arabidopsis tandem-pore K+ channel, poised to control the pollen membrane voltage in a pH- and Ca2+-dependent manner.” Becker D.et.al. 15505206 [4] “Members of the Arabidopsis AtTPK/KCO family form homomeric vacuolar channels in planta.” Voelker C.et.al. 16984403 [5] “TPK1, a Ca(2+)-regulated Arabidopsis vacuole two-pore K(+) channel is activated by 14-3-3 proteins.” Latz A.et.al. 17764516

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MEPLISPQPR FRLQPIPENP SSSSSSASIT IPRSISNTSF FHEISQERLL LHHQDLEQSV 
61:	QDDKEDQDSD SDETNRFLSQ TRPLHRSRTA PAMVIIKDLR TKPPETKKPS PVSKSIIRQA 
121:	IFLLIVYLTL GVSIYSFNRD HYSGIETHPV VDALYFCIVT MCTIGYGDIA PLTPWTKIFA 
181:	VVFVLFGFGF LDILLSGVVN YVLDLQESMI LTGIQTRQHH QHHHHHRFSA KDYIIDFEKG 
241:	RMRIRMKVCL ALCVVVLCIG VGALVLHFVE ELGFVDSVYL SVMSVTTVGY GDRAFKTLQG 
301:	RLFAAVWLLV STLAVARAFL YLAEARIDRR HRKAVKLALN REITVDDLLK ADTYQHGFIS 
361:	KSEYIVLKLK EMGKITQKDI DQVVIQFEKL DPNQIGKITL PDLLGDPL

1.A.1.7.5
Two-pore potassium channel 5 (AtTPK5) (Calcium-activated outward-rectifying potassium channel 5, chloroplastic) (AtKCO5). Reviewed by González et al. 2014.

Cross database links:

Gene Ontology

References (5)

External Searches:

Analyze:

1.A.1.7.5Two-pore potassium channel 5 (AtTPK5) (Calcium-activated outward-rectifying potassium channel 5, chloroplastic) (AtKCO5). Reviewed by González et al. 2014.

Cross database links:

Gene Ontology

References (5)

External Searches:

Analyze:

1.A.1.7.5
Two-pore potassium channel 5 (AtTPK5) (Calcium-activated outward-rectifying potassium channel 5, chloroplastic) (AtKCO5). Reviewed by González et al. 2014.