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1.A.1.9.5 The TWiK family muscle K⁺ channel protein 18 (TWiK or Two-P domain K⁺ channel family) (controls muscle contraction and organismal movement; Kunkel et al., 2000)
Accession Number:	Q18120
Protein Name:	TWiK family of potassium channels protein 18 aka twk-18
Length:	461
Molecular Weight:	52746.00
Species:	Caenorhabditis elegans [6239]
Number of TMSs:	5
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate	potassium(1+)

RefSeq:	NP_509516.1
Entrez Gene ID:	181139
Pfam:	PF07885
KEGG:	cel:C24A3.6
Gene Ontology GO:0016021 C:integral to membrane GO:0005267 F:potassium channel activity GO:0006813 P:potassium ion transport
References (3) [1] “Mutants of a temperature-sensitive two-P domain potassium channel.” Kunkel M.T.et.al. 11027209 [2] “Genome sequence of the nematode C. elegans: a platform for investigating biology.” The C. elegans sequencing consortiumet.al. 9851916 [3] “Proteomics reveals N-linked glycoprotein diversity in Caenorhabditis elegans and suggests an atypical translocation mechanism for integral membrane proteins.” Kaji H.et.al. 17761667

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MAIVAQGVST ILTTFQKTFK GLLPLIILVA YTLLGAWIFW MIEGENEREM LIEQQKERDE 
61:	LIRRTVYKIN QLQIKRQRRL MTAEEEYNRT AKVLTTFQET LGIVPADMDK DIHWTFLGSI 
121:	FYCMTVYTTI GYGNIVPGTG WGRFATILYA FIGIPLTVLS LYCLGSLFAK GCKMLWRFFL 
181:	KSTRVVSKDL SNKISEAADN IEEGTTAITP SAEKTENNDD DLLSFPISGL LLITVIWVIF 
241:	CAVLFTFLEE WDFGTSLYFT LISFTTIGFG DILPSDYDFM PIVGVLLLIG LSLVSTVMTL 
301:	IQQQIEALAS GMKDNIDQEY ARALNEARED GEVDEHVDPE EDPENNKKSF DAVISRMNWS 
361:	KRGLYYLLPD SQKKELAKQS EKKMGRKSIK IQTDNDLLET LIREEILKAE LNNEMHKYTA 
421:	PRSSHQPKLV YSDVREKEVP IEVVRVEHFN HGNEDYLEHD I

1.A.1.9.5
The TWiK family muscle K⁺ channel protein 18 (TWiK or Two-P domain K⁺ channel family) (controls muscle contraction and organismal movement; Kunkel et al., 2000)

Cross database links:

Gene Ontology

References (3)

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1.A.1.9.5The TWiK family muscle K+ channel protein 18 (TWiK or Two-P domain K+ channel family) (controls muscle contraction and organismal movement; Kunkel et al., 2000)

Cross database links:

Gene Ontology

References (3)

External Searches:

Analyze:

1.A.1.9.5
The TWiK family muscle K⁺ channel protein 18 (TWiK or Two-P domain K⁺ channel family) (controls muscle contraction and organismal movement; Kunkel et al., 2000)